James G. Lyon
Edmonton, AB, Canada
Last Updated: 09/26/2026
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Found 25 publications
Altered immune and metabolic molecular pathways drive islet cell dysfunction in human type 1 diabetes.
Journal: The Journal of clinical investigation
Published: May 05, 2025
Persistent organic pollutant concentrations in human pancreas correlate with markers of beta cell dysfunction.
Journal: Nature communications
Published: April 29, 2025
TBL1X/TBL1XR1 govern β-cell identity through a PAX6-containing gene regulatory network.
Journal: Nature communications
Published: October 31, 2024
Scale up manufacturing approach for production of human induced pluripotent stem cell-derived islets using Vertical Wheel® bioreactors.
Journal: NPJ Regenerative medicine
Published: August 22, 2024
Human research islet cell culture outcomes at the Alberta Diabetes Institute IsletCore.
Journal: Islets
Published: August 04, 2024
HumanIslets: An integrated platform for human islet data access and analysis.
Journal: bioRxiv : the preprint server for biology
Published: July 01, 2024
HumanIslets.com: Improving accessibility, integration, and usability of human research islet data.
Journal: Cell metabolism
Published: June 27, 2024
Proteomic predictors of individualized nutrient-specific insulin secretion in health and disease.
Journal: medRxiv : the preprint server for health sciences
Published: March 18, 2024
Evaluating Islet Cell Isolation and Transplantation From Donors Following Medical Assistance in Dying.
Journal: Transplantation direct
Published: March 08, 2024
Proteomic predictors of individualized nutrient-specific insulin secretion in health and disease.
Journal: Cell metabolism
Published: September 13, 2023
Aging compromises human islet beta cell function and identity by decreasing transcription factor activity and inducing ER stress.
Journal: Science advances
Published: October 05, 2022
Impacts of the COVID-19 pandemic on a human research islet program.
Journal: Islets
Published: March 14, 2022
Last Updated: 09/26/2026