James Heyes

887 Great Northern Way
Vancouver, BC V5T4T5, Canada

Last Updated: 09/26/2026

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Found 23 publications

Programmable protein degraders enable selective knockdown of pathogenic β-catenin subpopulations in vitro and in vivo.

Programmable protein degraders enable selective knockdown of pathogenic β-catenin subpopulations in vitro and in vivo.

Journal: Science advances

Published: August 28, 2026

Preventive and therapeutic efficacy of mRNA/LNP vaccines encoding HPV16 E6 and E7 in an early-intervention HPV tumor mouse models.

Preventive and therapeutic efficacy of mRNA/LNP vaccines encoding HPV16 E6 and E7 in an early-intervention HPV tumor mouse models.

Journal: Human vaccines & immunotherapeutics

Published: June 16, 2026

Cross-serotype immunity elicited by a consensus dengue NS1 mRNA vaccine in mice.

Cross-serotype immunity elicited by a consensus dengue NS1 mRNA vaccine in mice.

Journal: PloS one

Published: May 21, 2026

Evaluation of lipid nanoparticle adjuvants with different PEG lipid ratios and phospholipid modifications in non-human primates.

Evaluation of lipid nanoparticle adjuvants with different PEG lipid ratios and phospholipid modifications in non-human primates.

Journal: Molecular therapy. Nucleic acids

Published: February 14, 2026

Preclinical evaluation of DENV1 mRNA vaccines in mice: Toward improved neutralizing antibody and T cell responses.

Preclinical evaluation of DENV1 mRNA vaccines in mice: Toward improved neutralizing antibody and T cell responses.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: October 18, 2025

mRNA vaccines targeting Leptospira immunoglobulin-like proteins confer partial protection in a hamster model of leptospirosis.

mRNA vaccines targeting Leptospira immunoglobulin-like proteins confer partial protection in a hamster model of leptospirosis.

Journal: Vaccine

Published: October 01, 2025

Optimal murine CD4+ T cell priming by mRNA-lipid nanoparticle vaccines requires endogenous antigen processing.

Optimal murine CD4+ T cell priming by mRNA-lipid nanoparticle vaccines requires endogenous antigen processing.

Journal: Nature communications

Published: August 27, 2025

Influenza B mosaic HA mRNA-LNP vaccines are cross-reactive and protective in mice.

Influenza B mosaic HA mRNA-LNP vaccines are cross-reactive and protective in mice.

Journal: Molecular therapy. Nucleic acids

Published: June 03, 2025

A heterologous prime-boost regimen using BCG and an mRNA encoding Ag85B heightens immune response in mice.

A heterologous prime-boost regimen using BCG and an mRNA encoding Ag85B heightens immune response in mice.

Journal: Biochemical and biophysical research communications

Published: May 16, 2025

Programmable protein degraders enable selective knockdown of pathogenic β-catenin subpopulations in vitro and in vivo.

Programmable protein degraders enable selective knockdown of pathogenic β-catenin subpopulations in vitro and in vivo.

Journal: bioRxiv : the preprint server for biology

Published: November 28, 2024

Effect of mRNA formulated with lipid nanoparticles on the transcriptomic and epigenetic profiles of F4/80+ liver-associated macrophages.

Effect of mRNA formulated with lipid nanoparticles on the transcriptomic and epigenetic profiles of F4/80+ liver-associated macrophages.

Journal: Scientific reports

Published: May 24, 2024

Tailoring the adjuvanticity of lipid nanoparticles by PEG lipid ratio and phospholipid modifications.

Tailoring the adjuvanticity of lipid nanoparticles by PEG lipid ratio and phospholipid modifications.

Journal: Nature nanotechnology

Published: April 27, 2024

Showing 1-12 of 23

Last Updated: 09/26/2026