James Keaney
1420, Belgium
Last Updated: 09/26/2026
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Found 19 publications
Translational molecular imaging and drug development in multiple sclerosis.
Journal: Theranostics
Published: June 14, 2025
Discovery of a Potent SARM1 Base-Exchange Inhibitor with In Vivo Efficacy.
Journal: Journal of medicinal chemistry
Published: March 18, 2025
SARM1 base-exchange inhibitors induce SARM1 activation and neurodegeneration at low doses.
Journal: npj drug discovery
Published: March 13, 2025
Fenebrutinib, a Bruton's tyrosine kinase inhibitor, blocks distinct human microglial signaling pathways.
Journal: Journal of neuroinflammation
Published: August 01, 2024
Myeloid and lymphoid expression of C9orf72 regulates IL-17A signaling in mice.
Journal: Science translational medicine
Published: January 31, 2024
Innate immune activation and aberrant function in the R6/2 mouse model and Huntington's disease iPSC-derived microglia.
Journal: Frontiers in molecular neuroscience
Published: March 21, 2023
Divergent functional outcomes of NLRP3 blockade downstream of multi-inflammasome activation: therapeutic implications for ALS.
Journal: Frontiers in immunology
Published: March 20, 2023
C9orf72 suppresses systemic and neural inflammation induced by gut bacteria.
Journal: Nature
Published: May 17, 2019
Inhibition of Bruton's Tyrosine Kinase Modulates Microglial Phagocytosis: Therapeutic Implications for Alzheimer's Disease.
Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology
Published: December 21, 2018
Neuropolypathology as a result of severe traumatic brain injury?
Journal: Clinical neuropathology
Published: October 20, 2018
Age-related changes in eye morphology and aqueous humor dynamics in DBA/2J mice using contrast-enhanced ocular MRI.
Journal: Magnetic resonance imaging
Published: October 01, 2018
A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target.
Journal: Nature communications
Published: May 30, 2018
Last Updated: 09/26/2026