James M. Croop

Pediatrics

705 Riley Hospital Dr
Indianapolis, IN 46202

Last Updated: 09/26/2026

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Found 13 publications

A Phase 1/2 Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric and Young Adult Solid Tumors.

A Phase 1/2 Study of Lenvatinib in Combination With Everolimus in Recurrent and Refractory Pediatric and Young Adult Solid Tumors.

Journal: Pediatric blood & cancer

Published: November 21, 2024

A phase 1 trial utilizing a pharmacokinetic endpoint to determine the optimal dose of ramucirumab in children and adolescents with relapsed or refractory solid tumors, including central nervous system tumors.

A phase 1 trial utilizing a pharmacokinetic endpoint to determine the optimal dose of ramucirumab in children and adolescents with relapsed or refractory solid tumors, including central nervous system tumors.

Journal: Pediatric blood & cancer

Published: August 02, 2023

A phase 1, first-in-child, multicenter study to evaluate the safety and efficacy of the oncolytic herpes virus talimogene laherparepvec in pediatric patients with advanced solid tumors.

A phase 1, first-in-child, multicenter study to evaluate the safety and efficacy of the oncolytic herpes virus talimogene laherparepvec in pediatric patients with advanced solid tumors.

Journal: Frontiers in pediatrics

Published: March 09, 2023

PRL2 Phosphatase Promotes Oncogenic KIT Signaling in Leukemia Cells through Modulating CBL Phosphorylation.

PRL2 Phosphatase Promotes Oncogenic KIT Signaling in Leukemia Cells through Modulating CBL Phosphorylation.

Journal: Molecular cancer research : MCR

Published: February 22, 2023

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371.

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371.

Journal: Blood

Published: April 11, 2022

Parents' Insights into Pediatric Oncology Phase I Clinical Trials: Experiences from Their Child's Participation.

Parents' Insights into Pediatric Oncology Phase I Clinical Trials: Experiences from Their Child's Participation.

Journal: Seminars in oncology nursing

Published: June 21, 2021

Evidence for BCR/ABL1-positive T-cell acute lymphoblastic leukemia arising in an early lymphoid progenitor cell.

Evidence for BCR/ABL1-positive T-cell acute lymphoblastic leukemia arising in an early lymphoid progenitor cell.

Journal: Pediatric blood & cancer

Published: February 07, 2019

Phosphatase PRL2 promotes oncogenic NOTCH1-Induced T-cell leukemia.

Phosphatase PRL2 promotes oncogenic NOTCH1-Induced T-cell leukemia.

Journal: Leukemia

Published: November 23, 2016

Fever and neutropenia hospital discharges in children with cancer: A 2012 update.

Fever and neutropenia hospital discharges in children with cancer: A 2012 update.

Journal: Pediatric hematology and oncology

Published: February 23, 2016

Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial.

Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial.

Journal: The Lancet. Oncology

Published: October 27, 2012

Clinical course of postthrombotic syndrome in children with history of venous thromboembolism.

Clinical course of postthrombotic syndrome in children with history of venous thromboembolism.

Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis

Published: November 18, 2011

Gene therapy for fanconi anemia.

Gene therapy for fanconi anemia.

Journal: Current hematology reports

Published: August 07, 2003

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Last Updated: 09/26/2026