James P. O'gara

Gaillimh, C, Ireland

Last Updated: 09/26/2026

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Found 56 publications

Purine and pyrimidine analogs differentially regulate cell wall precursor biosynthesis to control β-lactam susceptibility in methicillin-resistant Staphylococcus aureus.

Purine and pyrimidine analogs differentially regulate cell wall precursor biosynthesis to control β-lactam susceptibility in methicillin-resistant Staphylococcus aureus.

Journal: mBio
Published: September 08, 2026

The β-lactam adjuvant guanosine potentiates anti-folate antibiotics and pyrimidine synthesis inhibitors by depleting thymidine in methicillin-resistant Staphylococcus aureus.

The β-lactam adjuvant guanosine potentiates anti-folate antibiotics and pyrimidine synthesis inhibitors by depleting thymidine in methicillin-resistant Staphylococcus aureus.

Journal: Antimicrobial agents and chemotherapy
Published: June 10, 2026

The β-lactam adjuvant guanosine potentiates anti-folate antibiotics and pyrimidine synthesis inhibitors by depleting thymidine in methicillin-resistant Staphylococcus aureus.

The β-lactam adjuvant guanosine potentiates anti-folate antibiotics and pyrimidine synthesis inhibitors by depleting thymidine in methicillin-resistant Staphylococcus aureus.

Journal: bioRxiv : the preprint server for biology
Published: February 06, 2026

Mutation of lipoprotein processing pathway gene lspA or inhibition of LspA activity by globomycin increases MRSA resistance to β-lactam antibiotics.

Mutation of lipoprotein processing pathway gene lspA or inhibition of LspA activity by globomycin increases MRSA resistance to β-lactam antibiotics.

Journal: Antimicrobial agents and chemotherapy
Published: December 29, 2025

Selective antimicrobial photodynamic therapy of clinical isolates from patients with infected diabetic foot ulcers using a small cationic chlorin.

Selective antimicrobial photodynamic therapy of clinical isolates from patients with infected diabetic foot ulcers using a small cationic chlorin.

Journal: Antimicrobial agents and chemotherapy
Published: November 18, 2025

A S180F substitution in D-alanine aminotransferase confers resistance to β-chloro-D-alanine in Staphylococcus aureus.

A S180F substitution in D-alanine aminotransferase confers resistance to β-chloro-D-alanine in Staphylococcus aureus.

Journal: The Journal of biological chemistry
Published: October 16, 2025

A D-alanine aminotransferase S180F substitution confers resistance to β-chloro-D-alanine in Staphylococcus aureus via antibiotic inactivation.

A D-alanine aminotransferase S180F substitution confers resistance to β-chloro-D-alanine in Staphylococcus aureus via antibiotic inactivation.

Journal: bioRxiv : the preprint server for biology
Published: September 02, 2025

Use of the bacteriophage-derived endolysin CHAPK-SH3blys as a potent novel treatment for biofilm-associated Staphylococcus aureus wound infections.

Use of the bacteriophage-derived endolysin CHAPK-SH3blys as a potent novel treatment for biofilm-associated Staphylococcus aureus wound infections.

Journal: Microbiology spectrum
Published: August 05, 2025

Clinical Signs and Symptoms of Biofilm in Chronic Wounds. What Do Practitioners Think? Consensus Through an Electronic Delphi Survey.

Clinical Signs and Symptoms of Biofilm in Chronic Wounds. What Do Practitioners Think? Consensus Through an Electronic Delphi Survey.

Journal: International wound journal
Published: June 24, 2025

Potent antimicrobial activity of hydrogel loaded with the antimicrobial peptide, D-Bac8c2,5 Leu, against monospecies and polymicrobial biofilms of Staphylococcus aureus and Pseudomonas aeruginosa.

Potent antimicrobial activity of hydrogel loaded with the antimicrobial peptide, D-Bac8c2,5 Leu, against monospecies and polymicrobial biofilms of Staphylococcus aureus and Pseudomonas aeruginosa.

Journal: Frontiers in microbiology
Published: February 06, 2025

A Scoping Review to Identify Clinical Signs, Symptoms and Biomarkers Reported in the Literature to Be Indicative of Biofilm in Chronic Wounds.

A Scoping Review to Identify Clinical Signs, Symptoms and Biomarkers Reported in the Literature to Be Indicative of Biofilm in Chronic Wounds.

Journal: International wound journal
Published: October 16, 2024

The pathogenicity and virulence of the opportunistic pathogen Staphylococcus epidermidis.

The pathogenicity and virulence of the opportunistic pathogen Staphylococcus epidermidis.

Journal: Virulence
Published: June 13, 2024
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Last Updated: 09/26/2026