James T. Yates

Oncology R&D
Cambridge, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 81 publications

Biparatopic targeting of IL-23 enables dual-epitope engagement and enhanced neutralization potency.

Biparatopic targeting of IL-23 enables dual-epitope engagement and enhanced neutralization potency.

Journal: mAbs

Published: June 17, 2026

The double-edged nature of antibody bivalency: mathematical and experimental analysis of cell surface antigen occupancy and opsonization.

The double-edged nature of antibody bivalency: mathematical and experimental analysis of cell surface antigen occupancy and opsonization.

Journal: mAbs

Published: June 03, 2026

TMDD Modeling for Antibodies Directed Against Soluble Targets: Parameter Values for De Novo Modeling and Simulation From Experimental Data.

TMDD Modeling for Antibodies Directed Against Soluble Targets: Parameter Values for De Novo Modeling and Simulation From Experimental Data.

Journal: Clinical pharmacology and therapeutics

Published: November 25, 2025

PBPK Modelling of PROTACs: Learnings from ARV-110 as a Case Example.

PBPK Modelling of PROTACs: Learnings from ARV-110 as a Case Example.

Journal: The AAPS journal

Published: October 08, 2025

A hybrid PKPD agent-based model of the tumour immune interaction: effects of anti-cancer combination therapy.

A hybrid PKPD agent-based model of the tumour immune interaction: effects of anti-cancer combination therapy.

Journal: Journal of pharmacokinetics and pharmacodynamics

Published: September 04, 2025

Understanding antibody-target antigen interactions and the avidity effect using mathematical modelling.

Understanding antibody-target antigen interactions and the avidity effect using mathematical modelling.

Journal: Journal of the Royal Society, Interface

Published: July 08, 2025

Physiologically-Based Pharmacokinetic Modeling to Support Pediatric Clinical Development: An IQ Working Group Perspective on the Current Status and Challenges.

Physiologically-Based Pharmacokinetic Modeling to Support Pediatric Clinical Development: An IQ Working Group Perspective on the Current Status and Challenges.

Journal: CPT: pharmacometrics & systems pharmacology

Published: May 30, 2025

Quantifying antibody binding: techniques and therapeutic implications.

Quantifying antibody binding: techniques and therapeutic implications.

Journal: mAbs

Published: February 17, 2025

An Asymptotic Analysis of Bivalent Monoclonal Antibody-Antigen Binding.

An Asymptotic Analysis of Bivalent Monoclonal Antibody-Antigen Binding.

Journal: Bulletin of mathematical biology

Published: January 17, 2025

A Mixed-Methods Cluster Randomised Waitlist-Controlled Trial of a Goal-Based Behaviour Change Intervention Implemented in Workplaces.

A Mixed-Methods Cluster Randomised Waitlist-Controlled Trial of a Goal-Based Behaviour Change Intervention Implemented in Workplaces.

Journal: International journal of environmental research and public health

Published: December 20, 2024

The need for effective workplace interventions for ethnic minorities living with rheumatological conditions.

The need for effective workplace interventions for ethnic minorities living with rheumatological conditions.

Journal: Rheumatology (Oxford, England)

Published: October 07, 2024

A systematic review of allometric scaling exponents for IgG mAbs.

A systematic review of allometric scaling exponents for IgG mAbs.

Journal: Xenobiotica; the fate of foreign compounds in biological systems

Published: July 27, 2024

Showing 1-12 of 81

Last Updated: 09/26/2026