James W. Wisler

James W. Wisler

Cardiology
540 New Waverly Pl
Cary, NC 27518

Last Updated: 09/26/2026

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Found 14 publications

The β-arrestin-biased β-adrenergic receptor blocker carvedilol enhances skeletal muscle contractility.

The β-arrestin-biased β-adrenergic receptor blocker carvedilol enhances skeletal muscle contractility.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: May 17, 2020

β-arrestin 1 regulates β2-adrenergic receptor-mediated skeletal muscle hypertrophy and contractility.

β-arrestin 1 regulates β2-adrenergic receptor-mediated skeletal muscle hypertrophy and contractility.

Journal: Skeletal muscle
Published: September 21, 2018

Biased G Protein-Coupled Receptor Signaling: Changing the Paradigm of Drug Discovery.

Biased G Protein-Coupled Receptor Signaling: Changing the Paradigm of Drug Discovery.

Journal: Circulation
Published: May 31, 2018

β-Arrestin2 mediates progression of murine primary myelofibrosis.

β-Arrestin2 mediates progression of murine primary myelofibrosis.

Journal: JCI insight
Published: October 18, 2017

Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor.

Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor.

Journal: Nature chemical biology
Published: February 05, 2016

The role of β-arrestin2-dependent signaling in thoracic aortic aneurysm formation in a murine model of Marfan syndrome.

The role of β-arrestin2-dependent signaling in thoracic aortic aneurysm formation in a murine model of Marfan syndrome.

Journal: American journal of physiology. Heart and circulatory physiology
Published: April 22, 2015

Antithrombotic therapy: new areas to understand efficacy and bleeding.

Antithrombotic therapy: new areas to understand efficacy and bleeding.

Journal: Expert opinion on therapeutic targets
Published: October 28, 2014

Recent developments in biased agonism.

Recent developments in biased agonism.

Journal: Current opinion in cell biology
Published: October 14, 2013

Emerging paradigms in arterial thrombosis.

Emerging paradigms in arterial thrombosis.

Journal: Journal of thrombosis and thrombolysis
Published: September 19, 2013

MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors.

MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors.

Journal: The Journal of cell biology
Published: November 21, 2012

Challenges and opportunities in implementing pharmacogenomics testing in the clinics.

Challenges and opportunities in implementing pharmacogenomics testing in the clinics.

Journal: Personalized medicine
Published: August 01, 2012

A guidance pathway for the selection of novel anticoagulants in the treatment of atrial fibrillation.

A guidance pathway for the selection of novel anticoagulants in the treatment of atrial fibrillation.

Journal: Critical pathways in cardiology
Published: May 19, 2012
Showing 1-12 of 14

Last Updated: 09/26/2026