Jan Fiedler

Nikolai Fuchs Str. 1
Hannover, NI 30625, Germany

Last Updated: 09/26/2026

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Found 73 publications

Preclinical evaluation of cysteine protease-inhibitor aloxistatin (E64d) for heart failure therapy.

Preclinical evaluation of cysteine protease-inhibitor aloxistatin (E64d) for heart failure therapy.

Journal: Journal of molecular medicine (Berlin, Germany)

Published: November 21, 2025

Structure-Based Design of PROTACS for the Degradation of Soluble Epoxide Hydrolase.

Structure-Based Design of PROTACS for the Degradation of Soluble Epoxide Hydrolase.

Journal: Journal of medicinal chemistry

Published: June 18, 2025

Increase in mechanical load and pro-fibrotic stimulation leads to fibrotic and hypertrophic remodeling in porcine living myocardial slices.

Increase in mechanical load and pro-fibrotic stimulation leads to fibrotic and hypertrophic remodeling in porcine living myocardial slices.

Journal: Scientific reports

Published: June 13, 2025

Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.

Repurposing of the small-molecule adrenoreceptor-inhibitor carvedilol for treatment of the fibrotic lung.

Journal: Frontiers in pharmacology

Published: November 26, 2024

Automated High-Throughput Live Cell Monitoring of Scratch Wound Closure.

Automated High-Throughput Live Cell Monitoring of Scratch Wound Closure.

Journal: Biomedical engineering and computational biology

Published: July 02, 2024

Patient-specific hiPSC-derived cardiomyocytes indicate allelic and contractile imbalance as pathogenic factor in early-stage Hypertrophic Cardiomyopathy.

Patient-specific hiPSC-derived cardiomyocytes indicate allelic and contractile imbalance as pathogenic factor in early-stage Hypertrophic Cardiomyopathy.

Journal: Journal of molecular and cellular cardiology

Published: May 31, 2024

Single-nucleus RNA sequencing identifies cell-type-specific effects of sodium-glucose co-transporter 2 inhibitors in human myocardial slices.

Single-nucleus RNA sequencing identifies cell-type-specific effects of sodium-glucose co-transporter 2 inhibitors in human myocardial slices.

Journal: European heart journal

Published: April 05, 2024

Case Report: C-reactive protein apheresis in non-ST-elevation ACS-case series from the C-reactive protein apheresis in Acute Myocardial Infarction Registry.

Case Report: C-reactive protein apheresis in non-ST-elevation ACS-case series from the C-reactive protein apheresis in Acute Myocardial Infarction Registry.

Journal: Frontiers in cardiovascular medicine

Published: March 15, 2024

SGLT2 inhibitors attenuate endothelial to mesenchymal transition and cardiac fibroblast activation.

SGLT2 inhibitors attenuate endothelial to mesenchymal transition and cardiac fibroblast activation.

Journal: Scientific reports

Published: February 09, 2024

Ex vivo modelling of cardiac injury identifies ferroptosis-related pathways as a potential therapeutic avenue for translational medicine.

Ex vivo modelling of cardiac injury identifies ferroptosis-related pathways as a potential therapeutic avenue for translational medicine.

Journal: Journal of molecular and cellular cardiology

Published: January 25, 2024

The role of fibrosis in cardiomyopathies: An opportunity to develop novel biomarkers of disease activity.

The role of fibrosis in cardiomyopathies: An opportunity to develop novel biomarkers of disease activity.

Journal: Matrix biology : journal of the International Society for Matrix Biology

Published: October 16, 2023

Inhibition of miR-21: cardioprotective effects in human failing myocardium ex vivo.

Inhibition of miR-21: cardioprotective effects in human failing myocardium ex vivo.

Journal: European heart journal

Published: September 29, 2023

Showing 1-12 of 73

Last Updated: 09/26/2026