Jan H. Hoeijmakers

Utrecht, UT, Netherlands

Last Updated: 09/26/2026

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Found 24 publications

Expanding the landscape of nucleotide excision repair disorders: from discovery to therapy.

Expanding the landscape of nucleotide excision repair disorders: from discovery to therapy.

Journal: The Journal of clinical investigation
Published: November 17, 2025

Unraveling the intersection of aging and Parkinson's disease: a collaborative roadmap for advancing research models.

Unraveling the intersection of aging and Parkinson's disease: a collaborative roadmap for advancing research models.

Journal: NPJ Parkinson's disease
Published: June 25, 2025

Dietary Restriction Mitigates Vascular Aging, Modulates the cGAS-STING Pathway and Reverses Macrophage-Like VSMC Phenotypes in Progeroid DNA-Repair-Deficient Ercc1Δ /- Mice.

Dietary Restriction Mitigates Vascular Aging, Modulates the cGAS-STING Pathway and Reverses Macrophage-Like VSMC Phenotypes in Progeroid DNA-Repair-Deficient Ercc1Δ /- Mice.

Journal: Aging cell
Published: January 22, 2025

Clinical implications of nutritional interventions reducing calories, a systematic scoping review.

Clinical implications of nutritional interventions reducing calories, a systematic scoping review.

Journal: Clinical nutrition ESPEN
Published: May 23, 2024

Trichothiodystrophy-associated MPLKIP maintains DBR1 levels for proper lariat debranching and ectodermal differentiation.

Trichothiodystrophy-associated MPLKIP maintains DBR1 levels for proper lariat debranching and ectodermal differentiation.

Journal: EMBO molecular medicine
Published: May 10, 2023

Fasting before living-kidney donation: effect on donor well-being and postoperative recovery: study protocol of a multicenter randomized controlled trial.

Fasting before living-kidney donation: effect on donor well-being and postoperative recovery: study protocol of a multicenter randomized controlled trial.

Journal: Trials
Published: July 29, 2021

Activation of the DNA damage response in vivo in synucleinopathy models of Parkinson's disease.

Activation of the DNA damage response in vivo in synucleinopathy models of Parkinson's disease.

Journal: Cell death & disease
Published: January 29, 2018

DNA damage-induced replication stress results in PA200-proteasome-mediated degradation of acetylated histones.

DNA damage-induced replication stress results in PA200-proteasome-mediated degradation of acetylated histones.

Journal: EMBO reports
Published: November 30, 2017

Vitamin E Supplementation Reduces Cellular Loss in the Brain of a Premature Aging Mouse Model.

Vitamin E Supplementation Reduces Cellular Loss in the Brain of a Premature Aging Mouse Model.

Journal: The journal of prevention of Alzheimer's disease
Published: November 29, 2017

DNA damage-induced histone H1 ubiquitylation is mediated by HUWE1 and stimulates the RNF8-RNF168 pathway.

DNA damage-induced histone H1 ubiquitylation is mediated by HUWE1 and stimulates the RNF8-RNF168 pathway.

Journal: Scientific reports
Published: April 27, 2017

After surviving cancer, what about late life effects of the cure?

After surviving cancer, what about late life effects of the cure?

Journal: EMBO molecular medicine
Published: November 18, 2016

A signature of renal stress resistance induced by short-term dietary restriction, fasting, and protein restriction.

A signature of renal stress resistance induced by short-term dietary restriction, fasting, and protein restriction.

Journal: Scientific reports
Published: April 18, 2016
Showing 1-12 of 24

Last Updated: 09/26/2026