Jan Misik

Hradec Kralove, KR 50001, Czech Republic

Last Updated: 09/26/2026

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Found 27 publications

Pharmacological and toxicological in vitro and in vivo effect of higher doses of oxime reactivators.

Pharmacological and toxicological in vitro and in vivo effect of higher doses of oxime reactivators.

Journal: Toxicology and applied pharmacology

Published: July 28, 2019

Tacrine and its 7-methoxy derivate; time-change concentration in plasma and brain tissue and basic toxicological profile in rats.

Tacrine and its 7-methoxy derivate; time-change concentration in plasma and brain tissue and basic toxicological profile in rats.

Journal: Drug and chemical toxicology

Published: July 02, 2019

Simple validated method of LC-MS/MS determination of BZ agent in rat plasma samples.

Simple validated method of LC-MS/MS determination of BZ agent in rat plasma samples.

Journal: Drug testing and analysis

Published: June 05, 2019

The Concentration of Memantine in the Cerebrospinal Fluid of Alzheimer's Disease Patients and Its Consequence to Oxidative Stress Biomarkers.

The Concentration of Memantine in the Cerebrospinal Fluid of Alzheimer's Disease Patients and Its Consequence to Oxidative Stress Biomarkers.

Journal: Frontiers in pharmacology

Published: June 02, 2019

Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease.

Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease.

Journal: European journal of medicinal chemistry

Published: December 16, 2018

Oxidative stress induced by oxime reactivators of acetylcholinesterase in vitro.

Oxidative stress induced by oxime reactivators of acetylcholinesterase in vitro.

Journal: Toxicology in vitro : an international journal published in association with BIBRA

Published: August 28, 2018

Orexin supplementation in narcolepsy treatment: A review.

Orexin supplementation in narcolepsy treatment: A review.

Journal: Medicinal research reviews

Published: June 17, 2018

In vitro skin decontamination of paraoxon - wet-type cleansing effect of selected detergents.

In vitro skin decontamination of paraoxon - wet-type cleansing effect of selected detergents.

Journal: Cutaneous and ocular toxicology

Published: July 21, 2017

Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.

Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.

Journal: Molecules (Basel, Switzerland)

Published: July 03, 2017

The Evaluation of the Reactivating and Neuroprotective Efficacy of Two Newly Prepared Bispyridinium Oximes (K305, K307) in Tabun-Poisoned Rats-A Comparison with Trimedoxime and the Oxime K203.

The Evaluation of the Reactivating and Neuroprotective Efficacy of Two Newly Prepared Bispyridinium Oximes (K305, K307) in Tabun-Poisoned Rats-A Comparison with Trimedoxime and the Oxime K203.

Journal: Molecules (Basel, Switzerland)

Published: June 19, 2017

Cholinesterase Inhibitor 6-Chlorotacrine - In Vivo Toxicological Profile and Behavioural Effects.

Cholinesterase Inhibitor 6-Chlorotacrine - In Vivo Toxicological Profile and Behavioural Effects.

Journal: Current Alzheimer research

Published: May 16, 2017

The benefit of combinations of oximes for the ability of antidotal treatment to counteract sarin-induced brain damage in rats.

The benefit of combinations of oximes for the ability of antidotal treatment to counteract sarin-induced brain damage in rats.

Journal: BMC pharmacology & toxicology

Published: April 18, 2017

Showing 1-12 of 27

Last Updated: 09/26/2026