Jan Motlik

Libechov, ST, Czech Republic

Last Updated: 09/26/2026

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Found 59 publications

Subretinal injection in the USH1CR31∗ pig model leads to chorioretinal atrophy that limits evaluation of efficacy of an AAV-mediated gene therapy.

Subretinal injection in the USH1CR31∗ pig model leads to chorioretinal atrophy that limits evaluation of efficacy of an AAV-mediated gene therapy.

Journal: Experimental eye research
Published: March 27, 2026

Treatment of spinal injury muscle spasticity by spinal subpial AAV9-GAD65/VGAT delivery: An efficacy and safety study in rat, pig, and NHP.

Treatment of spinal injury muscle spasticity by spinal subpial AAV9-GAD65/VGAT delivery: An efficacy and safety study in rat, pig, and NHP.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy
Published: February 28, 2026

Corrigendum to 'Restored phagocytic ability of RPE patches derived from gene-corrected retinitis pigmentosa-hiPSCs on a biodegradable scaffold via clinical-grade protocol: Implications for autologous therapy' [Genes Dis (12) (2025) 101609].

Corrigendum to 'Restored phagocytic ability of RPE patches derived from gene-corrected retinitis pigmentosa-hiPSCs on a biodegradable scaffold via clinical-grade protocol: Implications for autologous therapy' [Genes Dis (12) (2025) 101609].

Journal: Genes & diseases
Published: January 16, 2026

Molecular features of a Huntington's disease knock-in minipig.

Molecular features of a Huntington's disease knock-in minipig.

Journal: Disease models & mechanisms
Published: December 17, 2025

Protocol for the isolation, culturing, and evaluation of primary Müller glial cells from pig retina as cellular models in health and disease.

Protocol for the isolation, culturing, and evaluation of primary Müller glial cells from pig retina as cellular models in health and disease.

Journal: STAR protocols
Published: November 14, 2025

Subretinal Injection Volume Correlates to Persistent Outer Retinal Thinning in the Pig Eye.

Subretinal Injection Volume Correlates to Persistent Outer Retinal Thinning in the Pig Eye.

Journal: Investigative ophthalmology & visual science
Published: November 13, 2025

Induced pluripotent stem cells from a transgenic minipig model of Huntington's disease reveal early metabolic changes.

Induced pluripotent stem cells from a transgenic minipig model of Huntington's disease reveal early metabolic changes.

Journal: Disease models & mechanisms
Published: July 28, 2025

Safety of Human USH1C Transgene Expression Following Subretinal Injection in Wild-Type Pigs.

Safety of Human USH1C Transgene Expression Following Subretinal Injection in Wild-Type Pigs.

Journal: Investigative ophthalmology & visual science
Published: January 21, 2025

A model for de novo pigmentation of amelanotic retinal pigment epithelial cells.

A model for de novo pigmentation of amelanotic retinal pigment epithelial cells.

Journal: Acta ophthalmologica
Published: January 03, 2025

Optimizing Subretinal Bleb Formation for Visual Streak Involvement in a Porcine Model for Retinal Gene Therapy.

Optimizing Subretinal Bleb Formation for Visual Streak Involvement in a Porcine Model for Retinal Gene Therapy.

Journal: Investigative ophthalmology & visual science
Published: October 28, 2024

Delivery of Human iPSC-Derived RPE Cells in Healthy Minipig Retina Results in Interaction Between Photoreceptors and Transplanted Cells.

Delivery of Human iPSC-Derived RPE Cells in Healthy Minipig Retina Results in Interaction Between Photoreceptors and Transplanted Cells.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: October 03, 2024

Feasibility of Direct Vitrectomy-Sparing Subretinal Injection for Gene Delivery in Large Animals.

Feasibility of Direct Vitrectomy-Sparing Subretinal Injection for Gene Delivery in Large Animals.

Journal: Current eye research
Published: April 26, 2024
Showing 1-12 of 59

Last Updated: 09/26/2026