Jan P. Dobert
Erlangen, BY, Germany
Last Updated: 09/26/2026
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Found 13 publications
Cryo-TEM structure of β-glucocerebrosidase in complex with its transporter LIMP-2.
Journal: Nature communications
Published: June 12, 2024
Recombinant cathepsins B and L promote α-synuclein clearance and restore lysosomal function in human and murine models with α-synuclein pathology.
Journal: Molecular neurodegeneration
Published: February 22, 2024
Activation and Purification of ß-Glucocerebrosidase by Exploiting its Transporter LIMP-2 - Implications for Novel Treatment Strategies in Gaucher's and Parkinson's Disease.
Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: February 15, 2024
Reciprocal effects of alpha-synuclein aggregation and lysosomal homeostasis in synucleinopathy models.
Journal: Translational neurodegeneration
Published: January 03, 2023
From Lysosomal Storage Disorders to Parkinson's Disease - Challenges and Opportunities.
Journal: Journal of molecular biology
Published: October 05, 2022
Cancer-type organic anion transporting polypeptide 1B3 (Ct-OATP1B3) is localized in lysosomes and mediates resistance against kinase inhibitors.
Journal: Molecular pharmacology
Published: April 08, 2022
The role of lysosomal cathepsins in neurodegeneration: Mechanistic insights, diagnostic potential and therapeutic approaches.
Journal: Biochimica et biophysica acta. Molecular cell research
Published: June 30, 2021
Corrigendum: Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties.
Journal: Frontiers in cell and developmental biology
Published: February 24, 2021
Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties.
Journal: Frontiers in cell and developmental biology
Published: July 09, 2020
Functional Characterization of Colon Cancer-Associated Mutations in ADAM17: Modifications in the Pro-Domain Interfere with Trafficking and Maturation.
Journal: International journal of molecular sciences
Published: April 20, 2019
Last Updated: 09/26/2026