Jan-philipp Machtens

Hannover, NI, Germany

Last Updated: 09/26/2026

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Found 32 publications

The ZBTB16/CUL3/ROC1 ubiquitin ligase drives the degradation of pathogenic pendrin (SLC26A4) protein variants.

The ZBTB16/CUL3/ROC1 ubiquitin ligase drives the degradation of pathogenic pendrin (SLC26A4) protein variants.

Journal: Journal of biomedical science

Published: March 08, 2026

N-glycans on SLC26A3 do not significantly alter plasma membrane or lipid raft trafficking, but appear to stabilize interdomain contacts to stimulate transport.

N-glycans on SLC26A3 do not significantly alter plasma membrane or lipid raft trafficking, but appear to stabilize interdomain contacts to stimulate transport.

Journal: American journal of physiology. Gastrointestinal and liver physiology

Published: October 10, 2025

SLC26A11 is an atypical solute carrier with dual transport-channel function mediating lysosomal sulfate transport.

SLC26A11 is an atypical solute carrier with dual transport-channel function mediating lysosomal sulfate transport.

Journal: Nature communications

Published: July 10, 2025

Calcium-activated chloride channel TMEM16A opens via pi-helical transition in transmembrane segment 4.

Calcium-activated chloride channel TMEM16A opens via pi-helical transition in transmembrane segment 4.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: April 29, 2025

Allosteric modulation of proton binding confers Cl- activation and glutamate selectivity to vesicular glutamate transporters.

Allosteric modulation of proton binding confers Cl- activation and glutamate selectivity to vesicular glutamate transporters.

Journal: PLoS computational biology

Published: October 16, 2024

Electrochemical coupling at the plasma membrane by mouse voltage-sensitive phosphatase requires association with basigin.

Electrochemical coupling at the plasma membrane by mouse voltage-sensitive phosphatase requires association with basigin.

Journal: Cell reports

Published: October 15, 2024

Editorial: Combining computational and experimental approaches to characterize ion channels and transporters.

Editorial: Combining computational and experimental approaches to characterize ion channels and transporters.

Journal: Frontiers in physiology

Published: October 12, 2023

Corrigendum: Diclofenac and other non-steroidal anti-inflammatory drugs (NSAIDs) are competitive antagonists of the human P2X3 receptor.

Corrigendum: Diclofenac and other non-steroidal anti-inflammatory drugs (NSAIDs) are competitive antagonists of the human P2X3 receptor.

Journal: Frontiers in pharmacology

Published: May 19, 2023

Apo state pore opening as functional basis of increased EAAT anion channel activity in episodic ataxia 6.

Apo state pore opening as functional basis of increased EAAT anion channel activity in episodic ataxia 6.

Journal: Frontiers in physiology

Published: January 18, 2023

Domain- and state-specific shape of the electric field tunes voltage sensing in voltage-gated sodium channels.

Domain- and state-specific shape of the electric field tunes voltage sensing in voltage-gated sodium channels.

Journal: Biophysical journal

Published: December 30, 2022

Elevator-like movements of prestin mediate outer hair cell electromotility.

Elevator-like movements of prestin mediate outer hair cell electromotility.

Journal: Nature communications

Published: December 13, 2022

Diclofenac and other non-steroidal anti-inflammatory drugs (NSAIDs) are competitive antagonists of the human P2X3 receptor.

Diclofenac and other non-steroidal anti-inflammatory drugs (NSAIDs) are competitive antagonists of the human P2X3 receptor.

Journal: Frontiers in pharmacology

Published: December 09, 2022

Showing 1-12 of 32

Last Updated: 09/26/2026