Jan Zitko

Hradec Kralove, KR 50003, Czech Republic

Last Updated: 09/26/2026

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Found 48 publications

Pyrazinamide-derived 1,2,3-triazoles: Antimicrobial evaluation, selective antimycobacterial activity and mechanism of action insights.

Pyrazinamide-derived 1,2,3-triazoles: Antimicrobial evaluation, selective antimycobacterial activity and mechanism of action insights.

Journal: European journal of medicinal chemistry
Published: April 06, 2026

Concentration-dependent SERS, DFT, NCI, and molecular dynamics investigation of N-(5-chloropyrazin-2-yl)-4-ethylbenzamide (CEB) adsorbed on silver colloid.

Concentration-dependent SERS, DFT, NCI, and molecular dynamics investigation of N-(5-chloropyrazin-2-yl)-4-ethylbenzamide (CEB) adsorbed on silver colloid.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Published: March 30, 2026

Novel Quinazolinones Active against Multidrug-Resistant Mycobacterium Tuberculosis: Synthesis, Antimicrobial Evaluation, and in Silico Exploration of Penicillin-Binding Protein 1A as a Potential Target.

Novel Quinazolinones Active against Multidrug-Resistant Mycobacterium Tuberculosis: Synthesis, Antimicrobial Evaluation, and in Silico Exploration of Penicillin-Binding Protein 1A as a Potential Target.

Journal: ChemMedChem
Published: February 24, 2025

A new bactericidal chlorinated derivative containing 2-aminooxazole potentiates antibacterial action of colistin against multidrug-resistant acinetobacter baumannii.

A new bactericidal chlorinated derivative containing 2-aminooxazole potentiates antibacterial action of colistin against multidrug-resistant acinetobacter baumannii.

Journal: Medical microbiology and immunology
Published: February 19, 2025

Investigating the Mechanism of Antimycobacterial and Antiproliferative Activity of (E)-N'-Benzylidenepyrazine-2-Carbohydrazides and their Derivatives.

Investigating the Mechanism of Antimycobacterial and Antiproliferative Activity of (E)-N'-Benzylidenepyrazine-2-Carbohydrazides and their Derivatives.

Journal: ChemMedChem
Published: January 31, 2025

Antimicrobial and Antiproliferative Properties of 2-Phenyl-N-(Pyridin-2-yl)acetamides.

Antimicrobial and Antiproliferative Properties of 2-Phenyl-N-(Pyridin-2-yl)acetamides.

Journal: Chemical biology & drug design
Published: September 03, 2024

The discovery of a new nonbile acid modulator of Takeda G protein-coupled receptor 5: An integrated computational approach.

The discovery of a new nonbile acid modulator of Takeda G protein-coupled receptor 5: An integrated computational approach.

Journal: Archiv der Pharmazie
Published: May 28, 2024

A hit expansion of 3-benzamidopyrazine-2-carboxamide: Toward inhibitors of prolyl-tRNA synthetase with antimycobacterial activity.

A hit expansion of 3-benzamidopyrazine-2-carboxamide: Toward inhibitors of prolyl-tRNA synthetase with antimycobacterial activity.

Journal: Archiv der Pharmazie
Published: March 05, 2024

N-Pyrazinylhydroxybenzamides as biologically active compounds: a hit-expansion study and antimicrobial evaluation.

N-Pyrazinylhydroxybenzamides as biologically active compounds: a hit-expansion study and antimicrobial evaluation.

Journal: Future medicinal chemistry
Published: October 25, 2023

Correction to "Hybridization Approach Toward Novel Antituberculars: Design, Synthesis, and Biological Evaluation of Compounds Combining Pyrazinamide and 4-Aminosalicylic Acid".

Correction to "Hybridization Approach Toward Novel Antituberculars: Design, Synthesis, and Biological Evaluation of Compounds Combining Pyrazinamide and 4-Aminosalicylic Acid".

Journal: ACS infectious diseases
Published: July 24, 2023

Antimycobacterial pyridine carboxamides: From design to in vivo activity.

Antimycobacterial pyridine carboxamides: From design to in vivo activity.

Journal: European journal of medicinal chemistry
Published: April 24, 2023

Correction: Juhás et al. Improving Antimicrobial Activity and Physico-Chemical Properties by Isosteric Replacement of 2-Aminothiazole with 2-Aminooxazole. Pharmaceuticals 2022, 15, 580.

Correction: Juhás et al. Improving Antimicrobial Activity and Physico-Chemical Properties by Isosteric Replacement of 2-Aminothiazole with 2-Aminooxazole. Pharmaceuticals 2022, 15, 580.

Journal: Pharmaceuticals (Basel, Switzerland)
Published: February 13, 2023
Showing 1-12 of 48

Last Updated: 09/26/2026