Jana Karasova-Zdarova

Hradec Kralove, KR 50001, Czech Republic

Last Updated: 09/26/2026

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Found 42 publications

Next-generation broad-spectrum reactivators for effective countermeasure against organophosphorus poisoning.

Next-generation broad-spectrum reactivators for effective countermeasure against organophosphorus poisoning.

Journal: Archives of toxicology
Published: October 29, 2025

Novel antitubercular agents based on 2,4-disubstituted 5-(aryl-2-ylmethyl)-5H-pyrrolo[3,2-d]pyrimidines.

Novel antitubercular agents based on 2,4-disubstituted 5-(aryl-2-ylmethyl)-5H-pyrrolo[3,2-d]pyrimidines.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: July 23, 2025

Novel pyrimidine derivatives as promising antimycobacterial agents.

Novel pyrimidine derivatives as promising antimycobacterial agents.

Journal: European journal of medicinal chemistry
Published: May 24, 2025

Multifunctional, Fluorene-Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.

Multifunctional, Fluorene-Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.

Journal: Angewandte Chemie (International ed. in English)
Published: October 23, 2024

Potent and reversible open-channel blocker of NMDA receptor derived from dizocilpine with enhanced membrane-to-channel inhibition.

Potent and reversible open-channel blocker of NMDA receptor derived from dizocilpine with enhanced membrane-to-channel inhibition.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: April 12, 2024

A-series agent A-234: initial in vitro and in vivo characterization.

A-series agent A-234: initial in vitro and in vivo characterization.

Journal: Archives of toxicology
Published: January 05, 2024

Wireless Monitoring of Gastrointestinal Transit Time, Intra-luminal pH, Pressure and Temperature in Experimental Pigs: A Pilot Study.

Wireless Monitoring of Gastrointestinal Transit Time, Intra-luminal pH, Pressure and Temperature in Experimental Pigs: A Pilot Study.

Journal: Acta medica (Hradec Kralove)
Published: June 29, 2023

Combination of acetylcholinesterase inhibitors and NMDA receptor antagonists increases survival rate in soman-poisoned mice.

Combination of acetylcholinesterase inhibitors and NMDA receptor antagonists increases survival rate in soman-poisoned mice.

Journal: Toxicology mechanisms and methods
Published: April 13, 2023

The effect of single and repeated doses of rivastigmine on gastric myoelectric activity in experimental pigs.

The effect of single and repeated doses of rivastigmine on gastric myoelectric activity in experimental pigs.

Journal: PloS one
Published: April 09, 2022

A systematic evaluation of the cucurbit[7]uril pharmacokinetics and toxicity after a single dose and short-term repeated administration in mice.

A systematic evaluation of the cucurbit[7]uril pharmacokinetics and toxicity after a single dose and short-term repeated administration in mice.

Journal: Archives of toxicology
Published: December 19, 2021

A Comparison of the Neuroprotective and Reactivating Efficacy of a Novel Bispyridinium Oxime K870 with Commonly Used Pralidoxime and the Oxime HI-6 in Tabun-Poisoned Rats.

A Comparison of the Neuroprotective and Reactivating Efficacy of a Novel Bispyridinium Oxime K870 with Commonly Used Pralidoxime and the Oxime HI-6 in Tabun-Poisoned Rats.

Journal: Acta medica (Hradec Kralove)
Published: November 15, 2021

Toxicity, pharmacokinetics, and effectiveness of the ortho-chlorinated bispyridinium oxime, K870.

Toxicity, pharmacokinetics, and effectiveness of the ortho-chlorinated bispyridinium oxime, K870.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Published: September 07, 2021
Showing 1-12 of 42

Last Updated: 09/26/2026