Jana Z. Karasova

Hradec Kralove, KR 50001, Czech Republic

Last Updated: 09/26/2026

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Found 29 publications

Novel tacrine-based multi-target directed Ligands: Enhancing cholinesterase inhibition, NMDA receptor antagonism, and CNS bioavailability for Alzheimer's disease treatment.

Novel tacrine-based multi-target directed Ligands: Enhancing cholinesterase inhibition, NMDA receptor antagonism, and CNS bioavailability for Alzheimer's disease treatment.

Journal: European journal of medicinal chemistry

Published: March 05, 2025

Correction: The effect of single and repeated doses of rivastigmine on gastric myoelectric activity in experimental pigs.

Correction: The effect of single and repeated doses of rivastigmine on gastric myoelectric activity in experimental pigs.

Journal: PloS one

Published: December 11, 2024

Dizocilpine derivatives as neuroprotective NMDA receptor antagonists without psychomimetic side effects.

Dizocilpine derivatives as neuroprotective NMDA receptor antagonists without psychomimetic side effects.

Journal: European journal of medicinal chemistry

Published: May 31, 2024

Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents.

Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents.

Journal: Archives of toxicology

Published: January 17, 2024

Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition.

Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition.

Journal: European journal of medicinal chemistry

Published: November 28, 2023

Corrigendum to "The measured CSF/plasma donepezil concentration ratio but not individually measured CSF and plasma concentrations significantly increase over 24 h after donepezil treatment in patients with Alzheimer's disease" [Biomed. Pharmacother. 159 (2023) 114223].

Corrigendum to "The measured CSF/plasma donepezil concentration ratio but not individually measured CSF and plasma concentrations significantly increase over 24 h after donepezil treatment in patients with Alzheimer's disease" [Biomed. Pharmacother. 159 (2023) 114223].

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: July 29, 2023

Development of submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation.

Development of submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation.

Journal: European journal of medicinal chemistry

Published: December 23, 2022

The measured CSF/plasma donepezil concentration ratio but not individually measured CSF and plasma concentrations significantly increase over 24 h after donepezil treatment in patients with Alzheimer's disease.

The measured CSF/plasma donepezil concentration ratio but not individually measured CSF and plasma concentrations significantly increase over 24 h after donepezil treatment in patients with Alzheimer's disease.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: November 07, 2022

Novel D2/5-HT receptor modulators related to cariprazine with potential implication to schizophrenia treatment.

Novel D2/5-HT receptor modulators related to cariprazine with potential implication to schizophrenia treatment.

Journal: European journal of medicinal chemistry

Published: January 03, 2022

Effect of Oxime Encapsulation on Acetylcholinesterase Reactivation: Pharmacokinetic Study of the Asoxime-Cucurbit[7]uril Complex in Mice Using Hydrophilic Interaction Liquid Chromatography-Mass Spectrometry.

Effect of Oxime Encapsulation on Acetylcholinesterase Reactivation: Pharmacokinetic Study of the Asoxime-Cucurbit[7]uril Complex in Mice Using Hydrophilic Interaction Liquid Chromatography-Mass Spectrometry.

Journal: Molecular pharmaceutics

Published: May 21, 2021

Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease.

Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease.

Journal: ACS chemical neuroscience

Published: April 14, 2021

Donepezil and Rivastigmine: Pharmacokinetic Profile and Brain-targeting After Intramuscular Administration in Rats.

Donepezil and Rivastigmine: Pharmacokinetic Profile and Brain-targeting After Intramuscular Administration in Rats.

Journal: Iranian journal of pharmaceutical research : IJPR

Published: March 08, 2021

Showing 1-12 of 29

Last Updated: 09/26/2026