Janet Brownlees

1-3 Burtonhole Lane, NW7 1AD
London, ENG, United Kingdom

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 11 publications

Dual targeting of the UPS and autophagy as a novel therapy for neurodegenerative proteinopathies.

Dual targeting of the UPS and autophagy as a novel therapy for neurodegenerative proteinopathies.

Journal: Frontiers in cellular neuroscience

Published: November 03, 2025

MitoTracker transfers from astrocytes to neurons independently of mitochondria.

MitoTracker transfers from astrocytes to neurons independently of mitochondria.

Journal: Cell reports methods

Published: July 09, 2025

Investigating Connectivity Deficits in Alzheimer's Disease Using a Novel 3D Bioprinted Model Designed to Quantify Neurite Outgrowth.

Investigating Connectivity Deficits in Alzheimer's Disease Using a Novel 3D Bioprinted Model Designed to Quantify Neurite Outgrowth.

Journal: Bioengineering (Basel, Switzerland)

Published: January 31, 2025

Deficiency in NPC2 results in disruption of mitochondria-late endosome/lysosomes contact sites and endo-lysosomal lipid dyshomeostasis.

Deficiency in NPC2 results in disruption of mitochondria-late endosome/lysosomes contact sites and endo-lysosomal lipid dyshomeostasis.

Journal: Scientific reports

Published: March 25, 2024

Disrupting the interaction between AMBRA1 and DLC1 prevents apoptosis while enhancing autophagy and mitophagy.

Disrupting the interaction between AMBRA1 and DLC1 prevents apoptosis while enhancing autophagy and mitophagy.

Journal: Biology open

Published: March 01, 2024

Thioridazine reverts the phenotype in cellular and Drosophila models of amyotrophic lateral sclerosis by enhancing TDP-43 aggregate clearance.

Thioridazine reverts the phenotype in cellular and Drosophila models of amyotrophic lateral sclerosis by enhancing TDP-43 aggregate clearance.

Journal: Neurobiology of disease

Published: December 17, 2020

Inhibition of IL-34 Unveils Tissue-Selectivity and Is Sufficient to Reduce Microglial Proliferation in a Model of Chronic Neurodegeneration.

Inhibition of IL-34 Unveils Tissue-Selectivity and Is Sufficient to Reduce Microglial Proliferation in a Model of Chronic Neurodegeneration.

Journal: Frontiers in immunology

Published: July 01, 2020

Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses.

Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses.

Journal: Scientific reports

Published: January 19, 2018

Catechols and 3-hydroxypyridones as inhibitors of the DNA repair complex ERCC1-XPF.

Catechols and 3-hydroxypyridones as inhibitors of the DNA repair complex ERCC1-XPF.

Journal: Bioorganic & medicinal chemistry letters

Published: June 24, 2015

N-Hydroxyimides and hydroxypyrimidinones as inhibitors of the DNA repair complex ERCC1-XPF.

N-Hydroxyimides and hydroxypyrimidinones as inhibitors of the DNA repair complex ERCC1-XPF.

Journal: Bioorganic & medicinal chemistry letters

Published: June 24, 2015

Alzheimer therapy with an antibody against N-terminal Abeta 4-X and pyroglutamate Abeta 3-X.

Alzheimer therapy with an antibody against N-terminal Abeta 4-X and pyroglutamate Abeta 3-X.

Journal: Scientific reports

Published: June 16, 2015

Showing 1-11 of 11

Last Updated: 09/26/2026