Janet Hoogstraate
AstraZeneca R&D
Soedertaelje, AB, Sweden
Soedertaelje, AB, Sweden
Last Updated: 09/26/2026
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Found 9 publications
Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2).
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Published: December 31, 2016
Optimizing DMPK Properties: Experiences from a Big Pharma DMPK Department.
Journal: Current drug metabolism
Published: June 02, 2015
Cytochrome p450 inhibitory properties of common efflux transporter inhibitors.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: January 08, 2014
Functional ATP-binding cassette drug efflux transporters in isolated human and rat hepatocytes significantly affect assessment of drug disposition.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: January 08, 2014
The impact of solute carrier (SLC) drug uptake transporter loss in human and rat cryopreserved hepatocytes on clearance predictions.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: January 08, 2014
Prediction of in vivo rat biliary drug clearance from an in vitro hepatocyte efflux model.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: January 08, 2014
Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).
Journal: Toxicological sciences : an official journal of the Society of Toxicology
Published: September 10, 2013
Showing 1-9 of 9
Last Updated: 09/26/2026