Janina Niggenaber
Dortmund, NW 44227, Germany
Last Updated: 09/26/2026
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Found 9 publications
Targeting KRASG13C with cyclic linker based inhibitors to explore warhead orientation.
Journal: Scientific reports
Published: February 14, 2025
Advancing TET Inhibitor Development: From Structural Insights to Biological Evaluation.
Journal: ACS medicinal chemistry letters
Published: January 22, 2025
Avapritinib-based SAR studies unveil a binding pocket in KIT and PDGFRA.
Journal: Nature communications
Published: July 11, 2023
Addressing the Osimertinib Resistance Mutation EGFR-L858R/C797S with Reversible Aminopyrimidines.
Journal: ACS medicinal chemistry letters
Published: December 08, 2022
Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type-Sparing Inhibitors.
Journal: Journal of medicinal chemistry
Published: April 29, 2022
Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach.
Journal: Journal of medicinal chemistry
Published: September 15, 2020
Complex Crystal Structures of EGFR with Third-Generation Kinase Inhibitors and Simultaneously Bound Allosteric Ligands.
Journal: ACS medicinal chemistry letters
Published: August 26, 2020
Structure Defines Function: Clinically Relevant Mutations in ErbB Kinases.
Journal: Journal of medicinal chemistry
Published: August 16, 2019
Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S.
Journal: Chemical science
Published: July 12, 2019
Showing 1-9 of 9
Last Updated: 09/26/2026