Janine Kutzsche

Juelich, NW, Germany

Last Updated: 09/26/2026

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Found 47 publications

Pharmacokinetic properties of the clinical drug candidate PRI-002 with regard to genotype, sex, age, dose-dependence and food effects in mice.

Pharmacokinetic properties of the clinical drug candidate PRI-002 with regard to genotype, sex, age, dose-dependence and food effects in mice.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Published: July 03, 2026

In-depth characterization of the CaV2.2-knockout mouse line.

In-depth characterization of the CaV2.2-knockout mouse line.

Journal: Scientific reports

Published: April 27, 2026

The Proteome of Human Amyloid Beta Oligomers.

The Proteome of Human Amyloid Beta Oligomers.

Journal: Biochemistry

Published: January 14, 2026

Elucidation of the influence of the CaV2.2 calcium channel on ALS disease progression in the SOD1*G93A mouse model.

Elucidation of the influence of the CaV2.2 calcium channel on ALS disease progression in the SOD1*G93A mouse model.

Journal: Neurobiology of disease

Published: January 08, 2026

Oral PRI-002 treatment in patients with MCI or mild AD: a randomized, double-blind phase 1b trial.

Oral PRI-002 treatment in patients with MCI or mild AD: a randomized, double-blind phase 1b trial.

Journal: Nature communications

Published: November 11, 2024

Direct disassembly of α-syn preformed fibrils into α-syn monomers by an all-D-peptide.

Direct disassembly of α-syn preformed fibrils into α-syn monomers by an all-D-peptide.

Journal: NPJ Parkinson's disease

Published: September 03, 2024

Aβ oligomers peak in early stages of Alzheimer's disease preceding tau pathology.

Aβ oligomers peak in early stages of Alzheimer's disease preceding tau pathology.

Journal: Alzheimer's & dementia (Amsterdam, Netherlands)

Published: December 19, 2023

Blood-based quantification of Aβ oligomers indicates impaired clearance from brain in ApoE ε4 positive subjects.

Blood-based quantification of Aβ oligomers indicates impaired clearance from brain in ApoE ε4 positive subjects.

Journal: Communications medicine

Published: July 03, 2023

Elevated Aβ aggregates in feces from Alzheimer's disease patients: a proof-of-concept study.

Elevated Aβ aggregates in feces from Alzheimer's disease patients: a proof-of-concept study.

Journal: Alzheimer's research & therapy

Published: June 27, 2023

An orally available Cav2.2 calcium channel inhibitor for the treatment of neuropathic pain.

An orally available Cav2.2 calcium channel inhibitor for the treatment of neuropathic pain.

Journal: British journal of pharmacology

Published: May 31, 2023

Oral Treatment with d-RD2RD2 Impedes Early Disease Mechanisms in SOD1*G93A Transgenic Mice but Does Not Prolong Survival.

Oral Treatment with d-RD2RD2 Impedes Early Disease Mechanisms in SOD1*G93A Transgenic Mice but Does Not Prolong Survival.

Journal: Biomedicines

Published: February 27, 2023

Oral treatment with the all-d-peptide RD2 enhances cognition in aged beagle dogs - A model of sporadic Alzheimer's disease.

Oral treatment with the all-d-peptide RD2 enhances cognition in aged beagle dogs - A model of sporadic Alzheimer's disease.

Journal: Heliyon

Published: January 24, 2023

Showing 1-12 of 47

Last Updated: 09/26/2026