Janita J. Oosterhoff

Utrecht, UT, Netherlands

Last Updated: 09/26/2026

Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 10 publications

Structural basis of HPA-1a alloimmunization in FNAIT and allosteric regulation of integrin conformation.

Structural basis of HPA-1a alloimmunization in FNAIT and allosteric regulation of integrin conformation.

Journal: Blood
Published: November 25, 2025

Structural Basis of HPA-1a Alloimmunization in FNAIT and Allosteric Regulation of Integrin Conformation.

Structural Basis of HPA-1a Alloimmunization in FNAIT and Allosteric Regulation of Integrin Conformation.

Journal: Blood
Published: November 25, 2025

Maternal anti-HPA-1a antibodies block αIIbβ3 and αvβ3 integrin activation which correlates with FNAIT disease severity.

Maternal anti-HPA-1a antibodies block αIIbβ3 and αvβ3 integrin activation which correlates with FNAIT disease severity.

Journal: Blood
Published: September 16, 2025

Maternal anti-HPA-1a antibodies block αIIbβ3/αvβ3 integrin activation, and blockade correlates with FNAIT disease severity.

Maternal anti-HPA-1a antibodies block αIIbβ3/αvβ3 integrin activation, and blockade correlates with FNAIT disease severity.

Journal: Blood
Published: September 16, 2025

Altered glycosylation profile of anti-HPA-1a-specific antibodies: insights from a prospective fetal and neonatal alloimmune thrombocytopenia cohort.

Altered glycosylation profile of anti-HPA-1a-specific antibodies: insights from a prospective fetal and neonatal alloimmune thrombocytopenia cohort.

Journal: Haematologica
Published: July 14, 2025

HPA-1a antibodies in FNAIT do not distinguish αvβ3 from αIIbβ3, and bind inactive integrins more strongly than active integrins.

HPA-1a antibodies in FNAIT do not distinguish αvβ3 from αIIbβ3, and bind inactive integrins more strongly than active integrins.

Journal: Blood
Published: April 15, 2025

Generation of human antibodies targeting human platelet antigen (HPA)-1a.

Generation of human antibodies targeting human platelet antigen (HPA)-1a.

Journal: Transfusion
Published: December 01, 2023

Afucosylated IgG responses in humans - structural clues to the regulation of humoral immunity.

Afucosylated IgG responses in humans - structural clues to the regulation of humoral immunity.

Journal: Trends in immunology
Published: July 05, 2022

Fc galactosylation of anti-platelet human IgG1 alloantibodies enhances complement activation on platelets.

Fc galactosylation of anti-platelet human IgG1 alloantibodies enhances complement activation on platelets.

Journal: Haematologica
Published: December 13, 2021

Logic-gated antibody pairs that selectively act on cells co-expressing two antigens.

Logic-gated antibody pairs that selectively act on cells co-expressing two antigens.

Journal: Nature biotechnology
Published: March 30, 2021
Showing 1-10 of 10

Last Updated: 09/26/2026