Jasmin C. Aschenbrenner

205 Nelson Mandela Drive
Bloemfontein, FS 9300, South Africa

Last Updated: 09/26/2026

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Found 16 publications

X-ray Crystallography-Guided Design and Synthesis of Cyclopentyl Heteroaryl Carboxylic Acid-Based Inhibitors of the SARS-CoV-2 Nsp3 Macrodomain (Mac1).

X-ray Crystallography-Guided Design and Synthesis of Cyclopentyl Heteroaryl Carboxylic Acid-Based Inhibitors of the SARS-CoV-2 Nsp3 Macrodomain (Mac1).

Journal: Journal of medicinal chemistry

Published: July 13, 2026

A Computational Community Blind Challenge on Pan-Coronavirus Drug Discovery Data.

A Computational Community Blind Challenge on Pan-Coronavirus Drug Discovery Data.

Journal: Journal of chemical information and modeling

Published: February 26, 2026

Crystallographic Fragment Screening of the Dengue Virus Polymerase Reveals Multiple Binding Sites for the Development of Non-nucleoside Antiflavivirals.

Crystallographic Fragment Screening of the Dengue Virus Polymerase Reveals Multiple Binding Sites for the Development of Non-nucleoside Antiflavivirals.

Journal: Journal of medicinal chemistry

Published: September 02, 2025

Crystal structure of fatty acid thioesterase A bound by 129 fragments provides diverse development opportunities.

Crystal structure of fatty acid thioesterase A bound by 129 fragments provides diverse development opportunities.

Journal: Pest management science

Published: May 20, 2025

Crystallographic fragment screening of the dengue virus polymerase reveals multiple binding sites for the development of non-nucleoside antiflavivirals.

Crystallographic fragment screening of the dengue virus polymerase reveals multiple binding sites for the development of non-nucleoside antiflavivirals.

Journal: bioRxiv : the preprint server for biology

Published: April 16, 2025

Crystallographic fragment screening and deep mutational scanning of Zika virus NS2B-NS3 protease enable development of resistance-resilient inhibitors.

Crystallographic fragment screening and deep mutational scanning of Zika virus NS2B-NS3 protease enable development of resistance-resilient inhibitors.

Journal: Research square

Published: February 24, 2025

Combined crystallographic fragment screening and deep mutational scanning enable discovery of Zika virus NS2B-NS3 protease inhibitors.

Combined crystallographic fragment screening and deep mutational scanning enable discovery of Zika virus NS2B-NS3 protease inhibitors.

Journal: Nature communications

Published: January 21, 2025

Crystallographic fragment screening reveals ligand hotspots in TRIM21 PRY-SPRY domain.

Crystallographic fragment screening reveals ligand hotspots in TRIM21 PRY-SPRY domain.

Journal: Communications chemistry

Published: December 28, 2024

Identifying novel chemical matter against the Chikungunya virus nsP3 macrodomain through crystallographic fragment screening.

Identifying novel chemical matter against the Chikungunya virus nsP3 macrodomain through crystallographic fragment screening.

Journal: bioRxiv : the preprint server for biology

Published: September 04, 2024

Discovery of potent SARS-CoV-2 nsp3 macrodomain inhibitors uncovers lack of translation to cellular antiviral response.

Discovery of potent SARS-CoV-2 nsp3 macrodomain inhibitors uncovers lack of translation to cellular antiviral response.

Journal: bioRxiv : the preprint server for biology

Published: September 04, 2024

Crystallographic fragment screening and deep mutational scanning of Zika virus NS2B-NS3 protease enable development of resistance-resilient inhibitors.

Crystallographic fragment screening and deep mutational scanning of Zika virus NS2B-NS3 protease enable development of resistance-resilient inhibitors.

Journal: bioRxiv : the preprint server for biology

Published: May 15, 2024

High-throughput crystallographic fragment screening of Zika virus NS3 Helicase.

High-throughput crystallographic fragment screening of Zika virus NS3 Helicase.

Journal: bioRxiv : the preprint server for biology

Published: May 15, 2024

Showing 1-12 of 16

Last Updated: 09/26/2026