Jason D. Matthews

Gastroenterology

135 W End Ave
Somerville, NJ 08876

Last Updated: 09/26/2026

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Found 29 publications

Single-cell and spatial transcriptomics across populations with perianal fistulizing Crohn's disease shows pro-inflammatory CD4+ macrophage involvement in disease progression.

Single-cell and spatial transcriptomics across populations with perianal fistulizing Crohn's disease shows pro-inflammatory CD4+ macrophage involvement in disease progression.

Journal: Cellular and molecular gastroenterology and hepatology

Published: March 23, 2026

Metabolic network analysis of Crohn's disease reveals sex- and age-specific cellular phenotypes.

Metabolic network analysis of Crohn's disease reveals sex- and age-specific cellular phenotypes.

Journal: Cell systems

Published: January 31, 2026

Metabolic network analysis of Crohn's disease reveals sex- and age-specific cellular phenotypes.

Metabolic network analysis of Crohn's disease reveals sex- and age-specific cellular phenotypes.

Journal: Cell systems

Published: May 05, 2025

A Myeloid Lineage Signifying Anti-tumor Necrosis Factor Resistance in Crohn's Disease.

A Myeloid Lineage Signifying Anti-tumor Necrosis Factor Resistance in Crohn's Disease.

Journal: Cellular and molecular gastroenterology and hepatology

Published: December 19, 2024

PTGER4 signaling regulates class IIa HDAC function and SPINK4 mRNA levels in rectal epithelial cells.

PTGER4 signaling regulates class IIa HDAC function and SPINK4 mRNA levels in rectal epithelial cells.

Journal: Cell communication and signaling : CCS

Published: July 24, 2024

Single-cell transcriptomics of rectal organoids from individuals with perianal fistulizing Crohn's disease reveals patient-specific signatures.

Single-cell transcriptomics of rectal organoids from individuals with perianal fistulizing Crohn's disease reveals patient-specific signatures.

Journal: Scientific reports

Published: July 02, 2024

Persistent Inflammation of the Rectum in Perianal Fistulizing Crohn's Disease Is Associated With Goblet Cell Function.

Persistent Inflammation of the Rectum in Perianal Fistulizing Crohn's Disease Is Associated With Goblet Cell Function.

Journal: Gastro hep advances

Published: June 27, 2023

Altered inflammatory mucosal signatures within their spatial and cellular context during active ileal Crohn's disease.

Altered inflammatory mucosal signatures within their spatial and cellular context during active ileal Crohn's disease.

Journal: JCI insight

Published: April 25, 2023

Characterization of Intestinal Mesenchymal Stromal Cells From Patients With Inflammatory Bowel Disease for Autologous Cell Therapy.

Characterization of Intestinal Mesenchymal Stromal Cells From Patients With Inflammatory Bowel Disease for Autologous Cell Therapy.

Journal: Stem cells translational medicine

Published: August 17, 2022

Assessing Cellular and Transcriptional Diversity of Ileal Mucosa Among Treatment-Naïve and Treated Crohn's Disease.

Assessing Cellular and Transcriptional Diversity of Ileal Mucosa Among Treatment-Naïve and Treated Crohn's Disease.

Journal: Inflammatory bowel diseases

Published: August 11, 2022

Complexity of Secretory Chemokines in Human Intestinal Organoid Cultures Ex Vivo.

Complexity of Secretory Chemokines in Human Intestinal Organoid Cultures Ex Vivo.

Journal: Gastro hep advances

Published: May 31, 2022

Identifying metabolic shifts in Crohn's disease using' omics-driven contextualized computational metabolic network models.

Identifying metabolic shifts in Crohn's disease using' omics-driven contextualized computational metabolic network models.

Journal: Scientific reports

Published: May 30, 2022

Showing 1-12 of 29

Last Updated: 09/26/2026