Javier Burgueno

Barcelona, CT, Spain

Last Updated: 09/26/2026

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Found 21 publications

In vitro models for neuropathic pain phenotypic screening in brain therapeutics.

In vitro models for neuropathic pain phenotypic screening in brain therapeutics.

Journal: Pharmacological research

Published: December 20, 2023

Development of a Novel σ1 Receptor Biosensor Based on Its Heterodimerization with Binding Immunoglobulin Protein in Living Cells.

Development of a Novel σ1 Receptor Biosensor Based on Its Heterodimerization with Binding Immunoglobulin Protein in Living Cells.

Journal: ACS chemical neuroscience

Published: May 16, 2023

EST79232 and EST79376, Two Novel Sigma-1 Receptor Ligands, Exert Neuroprotection on Models of Motoneuron Degeneration.

EST79232 and EST79376, Two Novel Sigma-1 Receptor Ligands, Exert Neuroprotection on Models of Motoneuron Degeneration.

Journal: International journal of molecular sciences

Published: May 16, 2022

Bispecific sigma-1 receptor antagonism and mu-opioid receptor partial agonism: WLB-73502, an analgesic with improved efficacy and safety profile compared to strong opioids.

Bispecific sigma-1 receptor antagonism and mu-opioid receptor partial agonism: WLB-73502, an analgesic with improved efficacy and safety profile compared to strong opioids.

Journal: Acta pharmaceutica Sinica. B

Published: April 13, 2022

Identification of Sodium Transients Through NaV1.5 Channels as Regulators of Differentiation in Immortalized Dorsal Root Ganglia Neurons.

Identification of Sodium Transients Through NaV1.5 Channels as Regulators of Differentiation in Immortalized Dorsal Root Ganglia Neurons.

Journal: Frontiers in cellular neuroscience

Published: November 16, 2021

Propionamide Derivatives as Dual μ-Opioid Receptor Agonists and σ1 Receptor Antagonists for the Treatment of Pain.

Propionamide Derivatives as Dual μ-Opioid Receptor Agonists and σ1 Receptor Antagonists for the Treatment of Pain.

Journal: Journal of medicinal chemistry

Published: July 08, 2021

Identification of Novel Regulators of Zalcitabine-Induced Neuropathic Pain.

Identification of Novel Regulators of Zalcitabine-Induced Neuropathic Pain.

Journal: ACS chemical neuroscience

Published: June 29, 2021

Development of a novel in vitro assay to screen for neuroprotective drugs against iatrogenic neurite shortening.

Development of a novel in vitro assay to screen for neuroprotective drugs against iatrogenic neurite shortening.

Journal: PloS one

Published: November 02, 2020

Discovery of EST73502, a Dual μ-Opioid Receptor Agonist and σ1 Receptor Antagonist Clinical Candidate for the Treatment of Pain.

Discovery of EST73502, a Dual μ-Opioid Receptor Agonist and σ1 Receptor Antagonist Clinical Candidate for the Treatment of Pain.

Journal: Journal of medicinal chemistry

Published: October 16, 2020

A New Model of Sensorial Neuron-Like Cells for HTS of Novel Analgesics for Neuropathic Pain.

A New Model of Sensorial Neuron-Like Cells for HTS of Novel Analgesics for Neuropathic Pain.

Journal: SLAS discovery : advancing life sciences R & D

Published: November 02, 2018

A Complementary Scale of Biased Agonism for Agonists with Differing Maximal Responses.

A Complementary Scale of Biased Agonism for Agonists with Differing Maximal Responses.

Journal: Scientific reports

Published: May 26, 2017

Pharmacological Modulation of the Sigma 1 Receptor and the Treatment of Pain.

Pharmacological Modulation of the Sigma 1 Receptor and the Treatment of Pain.

Journal: Advances in experimental medicine and biology

Published: March 19, 2017

Showing 1-12 of 21

Last Updated: 09/26/2026