Javier M. Di Noia

Montreal, QC H3C3J7, Canada

Last Updated: 09/26/2026

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Found 45 publications

Ptpn2 limits plasma cell fate and antiviral immunity by integrating B cell receptor and IFN-γ signals in B cells.

Ptpn2 limits plasma cell fate and antiviral immunity by integrating B cell receptor and IFN-γ signals in B cells.

Journal: Science advances

Published: August 19, 2026

Addendum: Protein arginine methyltransferase 1 regulates B cell fate after positive selection in the germinal center in mice.

Addendum: Protein arginine methyltransferase 1 regulates B cell fate after positive selection in the germinal center in mice.

Journal: The Journal of experimental medicine

Published: November 10, 2025

Ubiquitination of MHC class II molecules regulates B-cell development and response to antigens in mice.

Ubiquitination of MHC class II molecules regulates B-cell development and response to antigens in mice.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: September 22, 2025

B cell receptor stimulation inhibits class switch recombination through elevated DNA repair.

B cell receptor stimulation inhibits class switch recombination through elevated DNA repair.

Journal: DNA repair

Published: August 22, 2025

CDADC1 is a vertebrate-specific dCTP deaminase that metabolizes gemcitabine and decitabine to prevent cellular toxicity.

CDADC1 is a vertebrate-specific dCTP deaminase that metabolizes gemcitabine and decitabine to prevent cellular toxicity.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: June 12, 2025

APOBEC2 safeguards skeletal muscle cell fate through binding chromatin and regulating transcription of non-muscle genes during myoblast differentiation.

APOBEC2 safeguards skeletal muscle cell fate through binding chromatin and regulating transcription of non-muscle genes during myoblast differentiation.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: April 16, 2024

B-cell intrinsic regulation of antibody mediated immunity by histone H2A deubiquitinase BAP1.

B-cell intrinsic regulation of antibody mediated immunity by histone H2A deubiquitinase BAP1.

Journal: Frontiers in immunology

Published: December 09, 2023

Conserved role of hnRNPL in alternative splicing of epigenetic modifiers enables B cell activation.

Conserved role of hnRNPL in alternative splicing of epigenetic modifiers enables B cell activation.

Journal: EMBO reports

Published: October 05, 2023

Unmutated but T cell dependent IgM antibodies targeting Streptococcus suis play an essential role in bacterial clearance.

Unmutated but T cell dependent IgM antibodies targeting Streptococcus suis play an essential role in bacterial clearance.

Journal: PLoS pathogens

Published: September 27, 2023

DOT1L activity limits transcription elongation velocity and favors RNAPII pausing to facilitate mutagenesis by AID.

DOT1L activity limits transcription elongation velocity and favors RNAPII pausing to facilitate mutagenesis by AID.

Journal: Nature communications

Published: June 12, 2023

RPA guides UNG to uracil in ssDNA to facilitate antibody class switching and repair of mutagenic uracil at the replication fork.

RPA guides UNG to uracil in ssDNA to facilitate antibody class switching and repair of mutagenic uracil at the replication fork.

Journal: Nucleic acids research

Published: March 31, 2023

Activation-induced cytidine deaminase expression by thymic B cells promotes T-cell tolerance and limits autoimmunity.

Activation-induced cytidine deaminase expression by thymic B cells promotes T-cell tolerance and limits autoimmunity.

Journal: iScience

Published: August 24, 2022

Showing 1-12 of 45

Last Updated: 09/26/2026