Javier Negueruela

Route De Lennik 808
Brussels, BRU 1070, Belgium

Last Updated: 09/26/2026

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Found 8 publications

PTPN2 deficiency amplifies inflammatory signalling and impairs functional maturation of human stem cell-derived islets.

PTPN2 deficiency amplifies inflammatory signalling and impairs functional maturation of human stem cell-derived islets.

Journal: Stem cell research & therapy

Published: July 22, 2025

Less severe endothelial injury and vascular pathway activation in SARS-CoV-2 Omicron variant compared to Alpha.

Less severe endothelial injury and vascular pathway activation in SARS-CoV-2 Omicron variant compared to Alpha.

Journal: Scientific reports

Published: June 03, 2025

Genome editing of TXNIP in human pluripotent stem cells for the generation of hepatocyte-like cells and insulin-producing islet-like aggregates.

Genome editing of TXNIP in human pluripotent stem cells for the generation of hepatocyte-like cells and insulin-producing islet-like aggregates.

Journal: Stem cell research & therapy

Published: December 30, 2024

Protocol for CRISPR-Cas12a genome editing of protein tyrosine phosphatases in human pluripotent stem cells and functional β-like cell generation.

Protocol for CRISPR-Cas12a genome editing of protein tyrosine phosphatases in human pluripotent stem cells and functional β-like cell generation.

Journal: STAR protocols

Published: June 28, 2024

PTPRK regulates glycolysis and de novo lipogenesis to promote hepatocyte metabolic reprogramming in obesity.

PTPRK regulates glycolysis and de novo lipogenesis to promote hepatocyte metabolic reprogramming in obesity.

Journal: Nature communications

Published: February 13, 2024

HAMSAB diet ameliorates dysfunctional signaling in pancreatic islets in autoimmune diabetes.

HAMSAB diet ameliorates dysfunctional signaling in pancreatic islets in autoimmune diabetes.

Journal: iScience

Published: April 17, 2023

Nova1 or Bim Deficiency in Pancreatic β-Cells Does Not Alter Multiple Low-Dose Streptozotocin-Induced Diabetes and Diet-Induced Obesity in Mice.

Nova1 or Bim Deficiency in Pancreatic β-Cells Does Not Alter Multiple Low-Dose Streptozotocin-Induced Diabetes and Diet-Induced Obesity in Mice.

Journal: Nutrients

Published: December 16, 2021

PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum Stress Response in Pancreatic β-Cells in Autoimmune Diabetes.

PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum Stress Response in Pancreatic β-Cells in Autoimmune Diabetes.

Journal: Diabetes

Published: May 21, 2021

Showing 1-8 of 8

Last Updated: 09/26/2026