Javier Orihuel

Madrid, MD, Spain

Last Updated: 09/26/2026

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Found 11 publications

Transitional initiatives for advancing the phasing out of the use of animals for drug and chemical safety testing: The IHI VICT3R project for reducing the use of animals by implementing virtual control groups.

Transitional initiatives for advancing the phasing out of the use of animals for drug and chemical safety testing: The IHI VICT3R project for reducing the use of animals by implementing virtual control groups.

Journal: NAM journal

Published: September 02, 2025

The long-term effects of adolescent Δ9-tetrahydrocannabinol on brain structure and function assessed through neuroimaging techniques in male and female rats.

The long-term effects of adolescent Δ9-tetrahydrocannabinol on brain structure and function assessed through neuroimaging techniques in male and female rats.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology

Published: December 29, 2022

Interaction between maternal immune activation and peripubertal stress in rats: impact on cocaine addiction-like behaviour, morphofunctional brain parameters and striatal transcriptome.

Interaction between maternal immune activation and peripubertal stress in rats: impact on cocaine addiction-like behaviour, morphofunctional brain parameters and striatal transcriptome.

Journal: Translational psychiatry

Published: August 23, 2022

Δ 9-Tetrahydrocannabinol During Adolescence Reprograms the Nucleus Accumbens Transcriptome, Affecting Reward Processing, Impulsivity, and Specific Aspects of Cocaine Addiction-Like Behavior in a Sex-Dependent Manner.

Δ 9-Tetrahydrocannabinol During Adolescence Reprograms the Nucleus Accumbens Transcriptome, Affecting Reward Processing, Impulsivity, and Specific Aspects of Cocaine Addiction-Like Behavior in a Sex-Dependent Manner.

Journal: The international journal of neuropsychopharmacology

Published: June 19, 2021

Cocaine-induced Fos expression in the rat brain: Modulation by prior Δ9-tetrahydrocannabinol exposure during adolescence and sex-specific effects.

Cocaine-induced Fos expression in the rat brain: Modulation by prior Δ9-tetrahydrocannabinol exposure during adolescence and sex-specific effects.

Journal: Brain research

Published: February 02, 2021

The effects of combined intravenous cocaine and ethanol self-administration on the behavioral and amino acid profile of young adult rats.

The effects of combined intravenous cocaine and ethanol self-administration on the behavioral and amino acid profile of young adult rats.

Journal: PloS one

Published: June 27, 2019

Ex vivo 1H-MRS brain metabolic profiling in a two-hit model of neurodevelopmental disorders: Prenatal immune activation and peripubertal stress.

Ex vivo 1H-MRS brain metabolic profiling in a two-hit model of neurodevelopmental disorders: Prenatal immune activation and peripubertal stress.

Journal: Schizophrenia research

Published: May 17, 2019

Impulsive Action and Impulsive Choice Are Differentially Associated With Gene Expression Variations of the GABAA Receptor Alfa 1 Subunit and the CB1 Receptor in the Lateral and Medial Orbitofrontal Cortices.

Impulsive Action and Impulsive Choice Are Differentially Associated With Gene Expression Variations of the GABAA Receptor Alfa 1 Subunit and the CB1 Receptor in the Lateral and Medial Orbitofrontal Cortices.

Journal: Frontiers in behavioral neuroscience

Published: November 08, 2018

MouBeAT: A New and Open Toolbox for Guided Analysis of Behavioral Tests in Mice.

MouBeAT: A New and Open Toolbox for Guided Analysis of Behavioral Tests in Mice.

Journal: Frontiers in behavioral neuroscience

Published: June 20, 2018

Central nucleus of the amygdala as a common substrate of the incubation of drug and natural reinforcer seeking.

Central nucleus of the amygdala as a common substrate of the incubation of drug and natural reinforcer seeking.

Journal: Addiction biology

Published: May 16, 2018

Unaltered cocaine self-administration in the prenatal LPS rat model of schizophrenia.

Unaltered cocaine self-administration in the prenatal LPS rat model of schizophrenia.

Journal: Progress in neuro-psychopharmacology & biological psychiatry

Published: February 02, 2016

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Last Updated: 09/26/2026