Javier S. Ruiz-Fernandez

Madrid, MD, Spain

Last Updated: 09/26/2026

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Found 106 publications

Resveratrol modulates pancreatic proteotoxic stress and metabolic dysfunction in human IAPP transgenic mice.

Resveratrol modulates pancreatic proteotoxic stress and metabolic dysfunction in human IAPP transgenic mice.

Journal: Frontiers in endocrinology

Published: May 03, 2026

Allosteric Modulation of the CB1 Receptor by a Juniper Berry Seasoning Extract: Deoxypodophyllotoxin as the Major Active Constituent.

Allosteric Modulation of the CB1 Receptor by a Juniper Berry Seasoning Extract: Deoxypodophyllotoxin as the Major Active Constituent.

Journal: Journal of agricultural and food chemistry

Published: February 21, 2026

Assessment of the therapeutic effect of IGS2.7, a CK1δ protein kinase inhibitor, in combination with riluzole for the treatment of ALS-associated TDP-43 proteinopathy.

Assessment of the therapeutic effect of IGS2.7, a CK1δ protein kinase inhibitor, in combination with riluzole for the treatment of ALS-associated TDP-43 proteinopathy.

Journal: Neuropharmacology

Published: October 04, 2025

Ageing, Neurodegeneration and the Endocannabinoid System.

Ageing, Neurodegeneration and the Endocannabinoid System.

Journal: Current topics in behavioral neurosciences

Published: July 24, 2025

Neurodegenerative Diseases: Pathogenesis and Preclinical Models for Translational Drug Discovery.

Neurodegenerative Diseases: Pathogenesis and Preclinical Models for Translational Drug Discovery.

Journal: Toxicologic pathology

Published: May 15, 2025

Preclinical evaluation of cannabidiolic acid as a neuroprotective agent in TDP-43 transgenic mice, an experimental model of amyotrophic lateral sclerosis.

Preclinical evaluation of cannabidiolic acid as a neuroprotective agent in TDP-43 transgenic mice, an experimental model of amyotrophic lateral sclerosis.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: April 14, 2025

Development of Novel Neuroprotective Agents Targeting GPCR Using in Vitro Assays.

Development of Novel Neuroprotective Agents Targeting GPCR Using in Vitro Assays.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: March 11, 2025

Relevance of a peripheral site of action outside the brain-blood barrier for the beneficial effects of CB2 receptor activation in experimental ALS in male mice.

Relevance of a peripheral site of action outside the brain-blood barrier for the beneficial effects of CB2 receptor activation in experimental ALS in male mice.

Journal: Cell communication and signaling : CCS

Published: January 27, 2025

Beneficial Effect of Dimethyl Fumarate Drug Repositioning in a Mouse Model of TDP-43-Dependent Frontotemporal Dementia.

Beneficial Effect of Dimethyl Fumarate Drug Repositioning in a Mouse Model of TDP-43-Dependent Frontotemporal Dementia.

Journal: Antioxidants (Basel, Switzerland)

Published: July 30, 2024

Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects.

Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche's Endocannabinoid System Projects.

Journal: Chimia

Published: June 09, 2024

Investigation in the cannabigerol derivative VCE-003.2 as a disease-modifying agent in a mouse model of experimental synucleinopathy.

Investigation in the cannabigerol derivative VCE-003.2 as a disease-modifying agent in a mouse model of experimental synucleinopathy.

Journal: Behavioral and brain functions : BBF

Published: May 20, 2024

Investigation in blood-brain barrier integrity and susceptibility to immune cell penetration in a mouse model of Dravet syndrome.

Investigation in blood-brain barrier integrity and susceptibility to immune cell penetration in a mouse model of Dravet syndrome.

Journal: Brain, behavior, & immunity - health

Published: April 01, 2024

Showing 1-12 of 106

Last Updated: 09/26/2026