Javier Valero-Robles

Salamanca, CL, Spain

Last Updated: 09/26/2026

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Found 17 publications

NG2-ITGA4 axis regulates Rho GTPases and leukemic aggressiveness in KMT2A-r B-ALL and is targetable with natalizumab.

NG2-ITGA4 axis regulates Rho GTPases and leukemic aggressiveness in KMT2A-r B-ALL and is targetable with natalizumab.

Journal: Blood
Published: September 19, 2025

Ribosomal protein deficiencies linked to Diamond-Blackfan anemia induce distinctive alterations of ATF4 expression.

Ribosomal protein deficiencies linked to Diamond-Blackfan anemia induce distinctive alterations of ATF4 expression.

Journal: iScience
Published: April 03, 2024

Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model.

Characterization of the spectrum of trivalent VAV1-mutation-driven tumours using a gene-edited mouse model.

Journal: Molecular oncology
Published: March 23, 2022

A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors.

A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors.

Journal: Cell reports
Published: September 17, 2021

VAV Proteins as Double Agents in Cancer: Oncogenes with Tumor Suppressor Roles.

VAV Proteins as Double Agents in Cancer: Oncogenes with Tumor Suppressor Roles.

Journal: Biology
Published: August 02, 2021

Distinct Roles of Vav Family Members in Adaptive and Innate Immune Models of Arthritis.

Distinct Roles of Vav Family Members in Adaptive and Innate Immune Models of Arthritis.

Journal: Biomedicines
Published: May 12, 2021

Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis.

Cancer-associated mutations in VAV1 trigger variegated signaling outputs and T-cell lymphomagenesis.

Journal: The EMBO journal
Published: February 25, 2021

Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor.

Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor.

Journal: Oncogene
Published: March 23, 2020

Computational and in vitro Pharmacodynamics Characterization of 1A-116 Rac1 Inhibitor: Relevance of Trp56 in Its Biological Activity.

Computational and in vitro Pharmacodynamics Characterization of 1A-116 Rac1 Inhibitor: Relevance of Trp56 in Its Biological Activity.

Journal: Frontiers in cell and developmental biology
Published: December 20, 2019

VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma.

VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma.

Journal: Nature communications
Published: March 06, 2019

Rho guanosine nucleotide exchange factors are not such bad guys after all in cancera.

Rho guanosine nucleotide exchange factors are not such bad guys after all in cancera.

Journal: Small GTPases
Published: January 10, 2018

An unexpected tumor suppressor role for VAV1a.

An unexpected tumor suppressor role for VAV1a.

Journal: Molecular & cellular oncology
Published: December 13, 2017
Showing 1-12 of 17

Last Updated: 09/26/2026