Jayanth S. Chandran
R&D, AstraZeneca
Cambridge, ENG, United Kingdom
Cambridge, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 10 publications
Pharmacokinetics of AAV9 Mediated Trastuzumab Expression in Rat Brain Following Systemic and Local Administration.
Journal: Journal of pharmaceutical sciences
Published: May 02, 2023
Assessment of AAV9 distribution and transduction in rats after administration through Intrastriatal, Intracisterna magna and Lumbar Intrathecal routes.
Journal: Gene therapy
Published: December 06, 2021
Current progress and limitations of AAV mediated delivery of protein therapeutic genes and the importance of developing quantitative pharmacokinetic/pharmacodynamic (PK/PD) models.
Journal: Advanced drug delivery reviews
Published: December 13, 2020
Gene Therapy in the Nervous System: Failures and Successes.
Journal: Advances in experimental medicine and biology
Published: August 26, 2017
Site Specific Modification of Adeno-Associated Virus Enables Both Fluorescent Imaging of Viral Particles and Characterization of the Capsid Interactome.
Journal: Scientific reports
Published: May 18, 2017
Viral delivery of C9orf72 hexanucleotide repeat expansions in mice leads to repeat-length-dependent neuropathology and behavioural deficits.
Journal: Disease models & mechanisms
Published: March 07, 2017
SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits.
Journal: Nature communications
Published: December 04, 2016
C9orf72 expansion disrupts ATM-mediated chromosomal break repair.
Journal: Nature neuroscience
Published: September 28, 2016
Perspectives on disrupted-inschizophrenia 1 signaling in neurogenesis.
Journal: Neural regeneration research
Published: February 11, 2015
Disc1 variation leads to specific alterations in adult neurogenesis.
Journal: PloS one
Published: April 04, 2014
Showing 1-10 of 10
Last Updated: 09/26/2026