Jean C. Dinh

Sheffield, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 14 publications

Developmental age and clinical illness drive in vivo variability of CYP1A2 ontogeny and caffeine metabolism in preterm neonates.

Developmental age and clinical illness drive in vivo variability of CYP1A2 ontogeny and caffeine metabolism in preterm neonates.

Journal: Frontiers in pharmacology

Published: March 05, 2026

The rational use of PBPK to assess the changing DDI liability in pediatrics: Model qualification and the move towards best practice.

The rational use of PBPK to assess the changing DDI liability in pediatrics: Model qualification and the move towards best practice.

Journal: Drug metabolism and pharmacokinetics

Published: September 29, 2025

Investigating Sulfotransferase Mediated Drug Interactions of Ethinylestradiol using a Physiologically Based Pharmacokinetic Model.

Investigating Sulfotransferase Mediated Drug Interactions of Ethinylestradiol using a Physiologically Based Pharmacokinetic Model.

Journal: The AAPS journal

Published: June 27, 2025

Development, Verification, and Application of a Chinese Pediatric Physiologically Based Pharmacokinetic Model: Emphasis on CYP Metabolism and Renal Elimination.

Development, Verification, and Application of a Chinese Pediatric Physiologically Based Pharmacokinetic Model: Emphasis on CYP Metabolism and Renal Elimination.

Journal: The AAPS journal

Published: May 15, 2025

Managing Drug-Drug Interactions Involving the Non-Prescription Opioid Loperamide Through Physiologically Based Pharmacokinetic Modeling.

Managing Drug-Drug Interactions Involving the Non-Prescription Opioid Loperamide Through Physiologically Based Pharmacokinetic Modeling.

Journal: CPT: pharmacometrics & systems pharmacology

Published: May 02, 2025

Development and Verification of Virtual Population Models for Predicting Drug Pharmacokinetics in Ethnic North American Populations.

Development and Verification of Virtual Population Models for Predicting Drug Pharmacokinetics in Ethnic North American Populations.

Journal: CPT: pharmacometrics & systems pharmacology

Published: January 24, 2025

Postpartum changes in maternal physiology and milk composition: a comprehensive database for developing lactation physiologically-based pharmacokinetic models.

Postpartum changes in maternal physiology and milk composition: a comprehensive database for developing lactation physiologically-based pharmacokinetic models.

Journal: Frontiers in pharmacology

Published: October 25, 2024

Physiologically Based Pharmacokinetic Modeling of Cannabidiol, Delta-9-Tetrahydrocannabinol, and Their Metabolites in Healthy Adults After Administration by Multiple Routes.

Physiologically Based Pharmacokinetic Modeling of Cannabidiol, Delta-9-Tetrahydrocannabinol, and Their Metabolites in Healthy Adults After Administration by Multiple Routes.

Journal: Clinical and translational science

Published: October 08, 2024

Prediction of Pediatric Pharmacokinetics for CYP3A4 Metabolized Drugs: Comparison of the Performance of Two Hepatic Ontogeny Within a Physiologically Based Pharmacokinetic Model.

Prediction of Pediatric Pharmacokinetics for CYP3A4 Metabolized Drugs: Comparison of the Performance of Two Hepatic Ontogeny Within a Physiologically Based Pharmacokinetic Model.

Journal: Journal of clinical pharmacology

Published: February 27, 2024

Combining data on the bioavailability of midazolam and physiologically-based pharmacokinetic modeling to investigate intestinal CYP3A4 ontogeny.

Combining data on the bioavailability of midazolam and physiologically-based pharmacokinetic modeling to investigate intestinal CYP3A4 ontogeny.

Journal: CPT: pharmacometrics & systems pharmacology

Published: February 01, 2024

Physiologically Based Pharmacokinetics Modeling in the Neonatal Population-Current Advances, Challenges, and Opportunities.

Physiologically Based Pharmacokinetics Modeling in the Neonatal Population-Current Advances, Challenges, and Opportunities.

Journal: Pharmaceutics

Published: September 26, 2023

Selective deuteration of bupropion slows epimerization and reduces metabolism.

Selective deuteration of bupropion slows epimerization and reduces metabolism.

Journal: Bioorganic & medicinal chemistry letters

Published: July 31, 2022

Showing 1-12 of 14

Last Updated: 09/26/2026