Jean-christophe Simard
Laval, QC, Canada
Last Updated: 09/26/2026
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Found 16 publications
PBI-4050 via GPR40 activation improves adenine-induced kidney injury in mice.
Journal: Clinical science (London, England : 1979)
Published: May 13, 2019
PBI-4050 Reduces Stellate Cell Activation and Liver Fibrosis through Modulation of Intracellular ATP Levels and the Liver Kinase B1/AMP-Activated Protein Kinase/Mammalian Target of Rapamycin Pathway.
Journal: The Journal of pharmacology and experimental therapeutics
Published: April 17, 2018
Quinoline-3-carboxamides such as tasquinimod are not specific inhibitors of S100A9.
Journal: Blood advances
Published: January 24, 2018
A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84.
Journal: The American journal of pathology
Published: August 11, 2017
Silver nanoparticles induce irremediable endoplasmic reticulum stress leading to unfolded protein response dependent apoptosis in breast cancer cells.
Journal: Apoptosis : an international journal on programmed cell death
Published: September 03, 2016
Activation of human AML14.3D10 eosinophils by nanoparticles: Modulatory activity on apoptosis and cytokine production.
Journal: Journal of immunotoxicology
Published: July 13, 2016
Silver nanoparticles of 70 nm and 20 nm affect differently the biology of human neutrophils.
Journal: Journal of immunotoxicology
Published: December 01, 2015
Prolonged cultures of unstimulated human neutrophils lead to the apparition and persistence of rest-in-plate structures (RIPs) recognized by professional phagocytes in vitro and in vivo.
Journal: The international journal of biochemistry & cell biology
Published: June 08, 2015
Gold nanoparticles induce apoptosis, endoplasmic reticulum stress events and cleavage of cytoskeletal proteins in human neutrophils.
Journal: Toxicology in vitro : an international journal published in association with BIBRA
Published: May 21, 2015
Silver nanoparticles rapidly induce atypical human neutrophil cell death by a process involving inflammatory caspases and reactive oxygen species and induce neutrophil extracellular traps release upon cell adhesion.
Journal: International immunopharmacology
Published: March 06, 2015
Silver nanoparticles induce degradation of the endoplasmic reticulum stress sensor activating transcription factor-6 leading to activation of the NLRP-3 inflammasome.
Journal: The Journal of biological chemistry
Published: January 17, 2015
Last Updated: 09/26/2026