Jean-claude Lacaille

Montreal, QC, Canada

Last Updated: 09/26/2026

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Found 53 publications

Cell Type-Specific mTORC1 Signaling and Translational Control in Synaptic Plasticity and Memory.

Cell Type-Specific mTORC1 Signaling and Translational Control in Synaptic Plasticity and Memory.

Journal: Journal of neurochemistry

Published: September 02, 2025

Dynamic and Homeostatic Neuron-Astrocyte Interactions at GABAergic Synapses.

Dynamic and Homeostatic Neuron-Astrocyte Interactions at GABAergic Synapses.

Journal: Neurochemical research

Published: July 24, 2025

Genetic Reduction of the Translational Repressors FMRP and 4E-BP2 Preserves Memory in Mouse Models of Alzheimer's Disease.

Genetic Reduction of the Translational Repressors FMRP and 4E-BP2 Preserves Memory in Mouse Models of Alzheimer's Disease.

Journal: Aging cell

Published: May 28, 2025

Hippocampal Inhibitory Interneuron-Specific DREADDs Treatment Alters mTORC1-4E-BP Signaling and Impairs Memory Formation.

Hippocampal Inhibitory Interneuron-Specific DREADDs Treatment Alters mTORC1-4E-BP Signaling and Impairs Memory Formation.

Journal: Journal of neurochemistry

Published: January 08, 2025

The ISR downstream target ATF4 represses long-term memory in a cell type-specific manner.

The ISR downstream target ATF4 represses long-term memory in a cell type-specific manner.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: July 24, 2024

Dysregulating mTORC1-4E-BP2 signaling in GABAergic interneurons impairs hippocampus-dependent learning and memory.

Dysregulating mTORC1-4E-BP2 signaling in GABAergic interneurons impairs hippocampus-dependent learning and memory.

Journal: Learning & memory (Cold Spring Harbor, N.Y.)

Published: April 22, 2024

Exploration of new space elicits phosphorylation of GluA1(Ser831) and S6K and expression of Arc in the hippocampus in vivo as in long-term potentiation.

Exploration of new space elicits phosphorylation of GluA1(Ser831) and S6K and expression of Arc in the hippocampus in vivo as in long-term potentiation.

Journal: Molecular brain

Published: January 17, 2024

The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer's disease.

The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer's disease.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: December 02, 2023

mRNA translation in astrocytes controls hippocampal long-term synaptic plasticity and memory.

mRNA translation in astrocytes controls hippocampal long-term synaptic plasticity and memory.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: November 28, 2023

Reversal of memory and autism-related phenotypes in Tsc2+/- mice via inhibition of Nlgn1.

Reversal of memory and autism-related phenotypes in Tsc2+/- mice via inhibition of Nlgn1.

Journal: Frontiers in cell and developmental biology

Published: April 13, 2023

mTORC1-mediated acquisition of reward-related representations by hippocampal somatostatin interneurons.

mTORC1-mediated acquisition of reward-related representations by hippocampal somatostatin interneurons.

Journal: Molecular brain

Published: February 27, 2023

Both GEF domains of the autism and developmental epileptic encephalopathy-associated Trio protein are required for proper tangential migration of GABAergic interneurons.

Both GEF domains of the autism and developmental epileptic encephalopathy-associated Trio protein are required for proper tangential migration of GABAergic interneurons.

Journal: Molecular psychiatry

Published: December 23, 2022

Showing 1-12 of 53

Last Updated: 09/26/2026