Jean-emmanuel E. Sarry

Toulouse, France

Last Updated: 09/26/2026

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Found 79 publications

Hitting AML where it breathes: the peroxisome fat trap.

Hitting AML where it breathes: the peroxisome fat trap.

Journal: Blood
Published: June 11, 2026

Glycolysis and glycolytic enzymes in acute myeloid leukemia: Warburg and beyond.

Glycolysis and glycolytic enzymes in acute myeloid leukemia: Warburg and beyond.

Journal: Frontiers in pharmacology
Published: March 04, 2026

LY3410738, a Covalent Inhibitor of Mutant IDH1/2, is Effective in Acute Myeloid Leukemia Preclinical Models.

LY3410738, a Covalent Inhibitor of Mutant IDH1/2, is Effective in Acute Myeloid Leukemia Preclinical Models.

Journal: Blood cancer discovery
Published: November 18, 2025

Non-genetic remodeling drives leukemia propagation and reveals actionable vulnerabilities in acute myeloid leukemia.

Non-genetic remodeling drives leukemia propagation and reveals actionable vulnerabilities in acute myeloid leukemia.

Journal: Cell reports. Medicine
Published: June 20, 2025

Therapeutic Potential of Glutaminase Inhibition Targeting Metabolic Adaptations in Resistant Melanomas to Targeted Therapy.

Therapeutic Potential of Glutaminase Inhibition Targeting Metabolic Adaptations in Resistant Melanomas to Targeted Therapy.

Journal: International journal of molecular sciences
Published: June 13, 2025

Metabolism and therapy in acute myeloid leukemia with isocitrate dehydrogenase 1/2 mutations

Metabolism and therapy in acute myeloid leukemia with isocitrate dehydrogenase 1/2 mutations

Journal: Medecine sciences : M/S
Published: April 28, 2025

Targeting systemic and tumor metabolic balances with ketogenic diets enhance efficacy of therapy in FLT3-ITD acute myeloid leukemia.

Targeting systemic and tumor metabolic balances with ketogenic diets enhance efficacy of therapy in FLT3-ITD acute myeloid leukemia.

Journal: Cell reports
Published: April 18, 2025

Adaptation of redox metabolism in drug-tolerant persister cells is a vulnerability to prevent relapse in pancreatic cancer.

Adaptation of redox metabolism in drug-tolerant persister cells is a vulnerability to prevent relapse in pancreatic cancer.

Journal: Oncogenesis
Published: March 06, 2025

Metformin induces ferroptosis associated with lipidomic remodeling in AML.

Metformin induces ferroptosis associated with lipidomic remodeling in AML.

Journal: Blood advances
Published: February 07, 2025

TP53-agnostic lethality through combined pan-HDAC and CDK inhibition in acute myeloid leukemia.

TP53-agnostic lethality through combined pan-HDAC and CDK inhibition in acute myeloid leukemia.

Journal: Cancer letters
Published: January 31, 2025

Multiomic integration reveals tumoral heterogeneity of lipid dependence within lethal group 3 medulloblastoma.

Multiomic integration reveals tumoral heterogeneity of lipid dependence within lethal group 3 medulloblastoma.

Journal: Cancer cell
Published: January 16, 2025

Chemoresistance of TP53 mutant acute myeloid leukemia requires the mevalonate byproduct, geranylgeranyl pyrophosphate, for induction of an adaptive stress response.

Chemoresistance of TP53 mutant acute myeloid leukemia requires the mevalonate byproduct, geranylgeranyl pyrophosphate, for induction of an adaptive stress response.

Journal: Leukemia
Published: December 05, 2024
Showing 1-12 of 79

Last Updated: 09/26/2026