Jean-francois Hernandez

Montpellier, France

Last Updated: 09/26/2026

Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 31 publications

Towards Improved Peptidic α-Ketoamide Inhibitors of the Plasmodial Subtilisin-Like SUB1: Exploration of N-Terminal Extensions and Cyclic Constraints.

Towards Improved Peptidic α-Ketoamide Inhibitors of the Plasmodial Subtilisin-Like SUB1: Exploration of N-Terminal Extensions and Cyclic Constraints.

Journal: ChemMedChem
Published: November 15, 2024

Insights from structure-activity relationships and the binding mode of peptidic α-ketoamide inhibitors of the malaria drug target subtilisin-like SUB1.

Insights from structure-activity relationships and the binding mode of peptidic α-ketoamide inhibitors of the malaria drug target subtilisin-like SUB1.

Journal: European journal of medicinal chemistry
Published: December 11, 2023

S-Ethyl-Isothiocitrullin-Based Dipeptides and 1,2,4-Oxadiazole Pseudo-Dipeptides: Solid Phase Synthesis and Evaluation as NO Synthase Inhibitors.

S-Ethyl-Isothiocitrullin-Based Dipeptides and 1,2,4-Oxadiazole Pseudo-Dipeptides: Solid Phase Synthesis and Evaluation as NO Synthase Inhibitors.

Journal: Molecules (Basel, Switzerland)
Published: June 02, 2023

Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates.

Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates.

Journal: Journal of medicinal chemistry
Published: November 30, 2022

Taylor dispersion analysis discloses the impairment of Aβ peptide aggregation by the presence of a fluorescent tag.

Taylor dispersion analysis discloses the impairment of Aβ peptide aggregation by the presence of a fluorescent tag.

Journal: Electrophoresis
Published: July 25, 2022

1,2,4-Triazole-3-thione analogues with an arylakyl group at position 4 as metallo-β-lactamase inhibitors.

1,2,4-Triazole-3-thione analogues with an arylakyl group at position 4 as metallo-β-lactamase inhibitors.

Journal: Bioorganic & medicinal chemistry
Published: March 29, 2022

Taylor Dispersion Analysis and Atomic Force Microscopy Provide a Quantitative Insight into the Aggregation Kinetics of Aβ (1-40)/Aβ (1-42) Amyloid Peptide Mixtures.

Taylor Dispersion Analysis and Atomic Force Microscopy Provide a Quantitative Insight into the Aggregation Kinetics of Aβ (1-40)/Aβ (1-42) Amyloid Peptide Mixtures.

Journal: ACS chemical neuroscience
Published: February 24, 2022

Synthesis and Characterization of Andrographolide Derivatives as Regulators of βAPP Processing in Human Cells.

Synthesis and Characterization of Andrographolide Derivatives as Regulators of βAPP Processing in Human Cells.

Journal: Molecules (Basel, Switzerland)
Published: November 18, 2021

1,2,4-Triazole-3-Thione Analogues with a 2-Ethylbenzoic Acid at Position 4 as VIM-type Metallo-β-Lactamase Inhibitors.

1,2,4-Triazole-3-Thione Analogues with a 2-Ethylbenzoic Acid at Position 4 as VIM-type Metallo-β-Lactamase Inhibitors.

Journal: ChemMedChem
Published: November 05, 2021

The C-terminal segment of Leishmania major HslU: Toward potential inhibitors of LmHslVU activity.

The C-terminal segment of Leishmania major HslU: Toward potential inhibitors of LmHslVU activity.

Journal: Bioorganic chemistry
Published: July 30, 2021

1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity.

1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity.

Journal: European journal of medicinal chemistry
Published: July 09, 2021

4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-β-lactamase inhibitors.

4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-β-lactamase inhibitors.

Journal: Bioorganic chemistry
Published: March 04, 2021
Showing 1-12 of 31

Last Updated: 09/26/2026