Jean-jacques Bourguignon
Strasbourg, France
Last Updated: 09/26/2026
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Found 26 publications
Convolamine, a tropane alkaloid extracted from Convolvulus plauricalis, is a potent sigma-1 receptor-positive modulator with cognitive and neuroprotective properties.
Journal: Phytotherapy research : PTR
Published: August 02, 2023
Coumarin Derivatives Exert Anti-Lung Cancer Activity by Inhibition of Epithelial-Mesenchymal Transition and Migration in A549 Cells.
Journal: Pharmaceuticals (Basel, Switzerland)
Published: November 20, 2021
Antiallodynic action of phosphodiesterase inhibitors in a mouse model of peripheral nerve injury.
Journal: Neuropharmacology
Published: July 05, 2021
Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model.
Journal: Molecules (Basel, Switzerland)
Published: December 03, 2020
Synthesis, Antileishmanial Activity and in silico Studies of Aminoguanidine Hydrazones (AGH) and Thiosemicarbazones (TSC) Against Leishmania chagasi Amastigotes.
Journal: Medicinal chemistry (Shariqah (United Arab Emirates))
Published: June 26, 2020
Indole-3-guanylhydrazone hydrochloride mitigates long-term cognitive impairment in a neonatal sepsis model with involvement of MAPK and NFκB pathways.
Journal: Neurochemistry international
Published: September 16, 2019
TSPO Ligands Boost Mitochondrial Function and Pregnenolone Synthesis.
Journal: Journal of Alzheimer's disease : JAD
Published: July 01, 2019
Design and synthesis of 3-aminophthalazine derivatives and structural analogues as PDE5 inhibitors: anti-allodynic effect against neuropathic pain in a mouse model.
Journal: European journal of medicinal chemistry
Published: January 21, 2019
Aminoguanidine Hydrazone Derivatives as Nonpeptide NPFF1 Receptor Antagonists Reverse Opioid Induced Hyperalgesia.
Journal: ACS chemical neuroscience
Published: May 05, 2018
Evidence for the involvement of TNF-α, IL-1β and IL-10 in the antinociceptive and anti-inflammatory effects of indole-3-guanylhydrazone hydrochloride, an aromatic aminoguanidine, in rodents.
Journal: Chemico-biological interactions
Published: January 21, 2018
Phenylpyridine-2-ylguanidines and rigid mimetics as novel inhibitors of TNFα overproduction: Beneficial action in models of neuropathic pain and of acute lung inflammation.
Journal: European journal of medicinal chemistry
Published: August 08, 2017
Efficient and Mild Ullmann-Type N-Arylation of Amides, Carbamates, and Azoles in Water.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany)
Published: February 21, 2017
Last Updated: 09/26/2026