Jean-jacques Medard

Lyon, France

Last Updated: 09/26/2026

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Found 29 publications

The Proinflammatory Secretome of Senescent Cells Can Be Controlled by a HIF2A-Dependent Upregulation and a FURIN-Dependent Cleavage of the ANGPTL4 Secreted Factor.

The Proinflammatory Secretome of Senescent Cells Can Be Controlled by a HIF2A-Dependent Upregulation and a FURIN-Dependent Cleavage of the ANGPTL4 Secreted Factor.

Journal: Aging cell
Published: January 22, 2025

A non-canonical role of ELN protects from cellular senescence by limiting iron-dependent regulation of gene expression.

A non-canonical role of ELN protects from cellular senescence by limiting iron-dependent regulation of gene expression.

Journal: Redox biology
Published: February 23, 2024

Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema.

Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema.

Journal: Aging
Published: April 25, 2023

Targeting chemoresistant senescent pancreatic cancer cells improves conventional treatment efficacy.

Targeting chemoresistant senescent pancreatic cancer cells improves conventional treatment efficacy.

Journal: Molecular biomedicine
Published: September 08, 2022

Transformed cells after senescence give rise to more severe tumor phenotypes than transformed non-senescent cells.

Transformed cells after senescence give rise to more severe tumor phenotypes than transformed non-senescent cells.

Journal: Cancer letters
Published: May 30, 2022

Physiology of PNS axons relies on glycolytic metabolism in myelinating Schwann cells.

Physiology of PNS axons relies on glycolytic metabolism in myelinating Schwann cells.

Journal: PloS one
Published: January 02, 2022

NF-κB-dependent secretome of senescent cells can trigger neuroendocrine transdifferentiation of breast cancer cells.

NF-κB-dependent secretome of senescent cells can trigger neuroendocrine transdifferentiation of breast cancer cells.

Journal: Aging cell
Published: July 21, 2021

Erratum to: Biallelic variants in HPDL cause pure and complicated hereditary spastic paraplegia.

Erratum to: Biallelic variants in HPDL cause pure and complicated hereditary spastic paraplegia.

Journal: Brain : a journal of neurology
Published: May 13, 2021

Biallelic variants in HPDL cause pure and complicated hereditary spastic paraplegia.

Biallelic variants in HPDL cause pure and complicated hereditary spastic paraplegia.

Journal: Brain : a journal of neurology
Published: July 24, 2020

PLA2R1 promotes DNA damage and inhibits spontaneous tumor formation during aging.

PLA2R1 promotes DNA damage and inhibits spontaneous tumor formation during aging.

Journal: Cell death & disease
Published: March 24, 2020

From Langmuir-Blodgett to Grafted Films.

From Langmuir-Blodgett to Grafted Films.

Journal: Langmuir : the ACS journal of surfaces and colloids
Published: February 20, 2020

Disrupted function of lactate transporter MCT1, but not MCT4, in Schwann cells affects the maintenance of motor end-plate innervation.

Disrupted function of lactate transporter MCT1, but not MCT4, in Schwann cells affects the maintenance of motor end-plate innervation.

Journal: Glia
Published: December 31, 2019
Showing 1-12 of 29

Last Updated: 09/26/2026