Jean-noel Octave

Brussels, BRU, Belgium

Last Updated: 09/26/2026

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Found 35 publications

Conditional deletion of KCC2 impairs synaptic plasticity and both spatial and nonspatial memory.

Conditional deletion of KCC2 impairs synaptic plasticity and both spatial and nonspatial memory.

Journal: Frontiers in molecular neuroscience

Published: October 27, 2022

CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia.

CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia.

Journal: Acta neuropathologica communications

Published: May 18, 2021

Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission.

Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission.

Journal: Scientific reports

Published: May 05, 2021

Regulation of PPARα by APP in Alzheimer disease affects the pharmacological modulation of synaptic activity.

Regulation of PPARα by APP in Alzheimer disease affects the pharmacological modulation of synaptic activity.

Journal: JCI insight

Published: March 30, 2021

Alzheimer's Disease, a Lipid Story: Involvement of Peroxisome Proliferator-Activated Receptor α.

Alzheimer's Disease, a Lipid Story: Involvement of Peroxisome Proliferator-Activated Receptor α.

Journal: Cells

Published: April 17, 2020

Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release.

Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release.

Journal: eNeuro

Published: August 14, 2019

Sex-regulated gene dosage effect of PPARα on synaptic plasticity.

Sex-regulated gene dosage effect of PPARα on synaptic plasticity.

Journal: Life science alliance

Published: November 30, 2018

Editorial: Risk Factors and Outcome Predicating Biomarker of Neurodegenerative Diseases.

Editorial: Risk Factors and Outcome Predicating Biomarker of Neurodegenerative Diseases.

Journal: Frontiers in neurology

Published: October 16, 2018

Influence of the familial Alzheimer's disease-associated T43I mutation on the transmembrane structure and γ-secretase processing of the C99 peptide.

Influence of the familial Alzheimer's disease-associated T43I mutation on the transmembrane structure and γ-secretase processing of the C99 peptide.

Journal: The Journal of biological chemistry

Published: October 07, 2018

Aggregated Tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo.

Aggregated Tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo.

Journal: Acta neuropathologica

Published: September 17, 2018

Contribution of the Endosomal-Lysosomal and Proteasomal Systems in Amyloid-β Precursor Protein Derived Fragments Processing.

Contribution of the Endosomal-Lysosomal and Proteasomal Systems in Amyloid-β Precursor Protein Derived Fragments Processing.

Journal: Frontiers in cellular neuroscience

Published: July 05, 2018

A Role for GDNF and Soluble APP as Biomarkers of Amyotrophic Lateral Sclerosis Pathophysiology.

A Role for GDNF and Soluble APP as Biomarkers of Amyotrophic Lateral Sclerosis Pathophysiology.

Journal: Frontiers in neurology

Published: February 28, 2018

Showing 1-12 of 35

Last Updated: 09/26/2026