Jean-philippe Gratton

Montreal, QC, Canada

Last Updated: 09/26/2026

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Found 21 publications

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression.

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression.

Journal: Cell reports

Published: August 01, 2026

Inhibition of PAK2 in endothelial cells suppresses tumor angiogenesis and promotes immune sensitization through CXCL10.

Inhibition of PAK2 in endothelial cells suppresses tumor angiogenesis and promotes immune sensitization through CXCL10.

Journal: Cell reports

Published: August 26, 2024

Selective activation of FZD2 and FZD7 reveals non-redundant function during mesoderm differentiation.

Selective activation of FZD2 and FZD7 reveals non-redundant function during mesoderm differentiation.

Journal: Stem cell reports

Published: June 06, 2024

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression.

The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression.

Journal: Cell reports

Published: December 15, 2023

ZO-1 interacts with YB-1 in endothelial cells to regulate stress granule formation during angiogenesis.

ZO-1 interacts with YB-1 in endothelial cells to regulate stress granule formation during angiogenesis.

Journal: Nature communications

Published: January 11, 2022

eNOS controls angiogenic sprouting and retinal neovascularization through the regulation of endothelial cell polarity.

eNOS controls angiogenic sprouting and retinal neovascularization through the regulation of endothelial cell polarity.

Journal: Cellular and molecular life sciences : CMLS

Published: July 24, 2021

Targeting Axl favors an antitumorigenic microenvironment that enhances immunotherapy responses by decreasing Hif-1α levels.

Targeting Axl favors an antitumorigenic microenvironment that enhances immunotherapy responses by decreasing Hif-1α levels.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: July 16, 2021

Rap1 is Involved in Angiopoietin-1-Induced Cell-Cell Junction Stabilization and Endothelial Cell Sprouting.

Rap1 is Involved in Angiopoietin-1-Induced Cell-Cell Junction Stabilization and Endothelial Cell Sprouting.

Journal: Cells

Published: November 22, 2019

Polarization and sprouting of endothelial cells by angiopoietin-1 require PAK2 and paxillin-dependent Cdc42 activation.

Polarization and sprouting of endothelial cells by angiopoietin-1 require PAK2 and paxillin-dependent Cdc42 activation.

Journal: Molecular biology of the cell

Published: May 30, 2019

NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy.

NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: February 22, 2019

AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple-negative breast cancer.

AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple-negative breast cancer.

Journal: Oncotarget

Published: October 03, 2018

AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network.

AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network.

Journal: Nature communications

Published: August 16, 2018

Showing 1-12 of 21

Last Updated: 09/26/2026