Jean-philippe Leyris
165, Rue Denis Papin
Montarnaud, 34570, France
Montarnaud, 34570, France
Last Updated: 09/26/2026
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Found 8 publications
FL/FLT3 signaling enhances mechanical pain hypersensitivity through Interleukin-1 beta (IL-1β) in male mice.
Journal: Neurobiology of pain (Cambridge, Mass.)
Published: July 29, 2025
FLT3 signaling inhibition abrogates opioid tolerance and hyperalgesia while preserving analgesia.
Journal: Nature communications
Published: December 06, 2023
Activation of neuronal FLT3 promotes exaggerated sensorial and emotional pain-related behaviors facilitating the transition from acute to chronic pain.
Journal: Progress in neurobiology
Published: July 04, 2022
High-Throughput Screening for Extracellular Inhibitors of the FLT3 Receptor Tyrosine Kinase Reveals Chemically Diverse and Druggable Negative Allosteric Modulators.
Journal: ACS chemical biology
Published: March 01, 2022
Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice.
Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice.
Journal: Nature communications
Published: May 12, 2017
Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling.
Journal: The Journal of biological chemistry
Published: April 20, 2015
Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: January 22, 2015
High constitutive activity is an intrinsic feature of ghrelin receptor protein: a study with a functional monomeric GHS-R1a receptor reconstituted in lipid discs.
Journal: The Journal of biological chemistry
Published: November 26, 2011
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Last Updated: 09/26/2026