Jean-philippe Loeffler

Strasbourg, France

Last Updated: 09/26/2026

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Found 38 publications

Erratum to "Links between COVID-19, long COVID, and neurodegeneration: The role of glycosphingolipids" [Pharmacological Reviews 78 (2026) 100113].

Erratum to "Links between COVID-19, long COVID, and neurodegeneration: The role of glycosphingolipids" [Pharmacological Reviews 78 (2026) 100113].

Journal: Pharmacological reviews
Published: May 20, 2026

Links between COVID-19, long COVID, and neurodegeneration: The role of glycosphingolipids.

Links between COVID-19, long COVID, and neurodegeneration: The role of glycosphingolipids.

Journal: Pharmacological reviews
Published: July 31, 2025

An open-label Phase 2a study to assess the safety and tolerability of trimetazidine in patients with amyotrophic lateral sclerosis.

An open-label Phase 2a study to assess the safety and tolerability of trimetazidine in patients with amyotrophic lateral sclerosis.

Journal: Brain communications
Published: November 08, 2024

Alteration of the Neuromuscular Junction and Modifications of Muscle Metabolism in Response to Neuron-Restricted Expression of the CHMP2Bintron5 Mutant in a Mouse Model of ALS-FTD Syndrome.

Alteration of the Neuromuscular Junction and Modifications of Muscle Metabolism in Response to Neuron-Restricted Expression of the CHMP2Bintron5 Mutant in a Mouse Model of ALS-FTD Syndrome.

Journal: Biomolecules
Published: December 14, 2021

Repurposing of Trimetazidine for amyotrophic lateral sclerosis: A study in SOD1G93A mice.

Repurposing of Trimetazidine for amyotrophic lateral sclerosis: A study in SOD1G93A mice.

Journal: British journal of pharmacology
Published: July 16, 2021

Skeletal Muscle Metabolism: Origin or Prognostic Factor for Amyotrophic Lateral Sclerosis (ALS) Development?

Skeletal Muscle Metabolism: Origin or Prognostic Factor for Amyotrophic Lateral Sclerosis (ALS) Development?

Journal: Cells
Published: May 02, 2021

Sphingolipids metabolism alteration in the central nervous system: Amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases.

Sphingolipids metabolism alteration in the central nervous system: Amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases.

Journal: Seminars in cell & developmental biology
Published: June 23, 2020

Drug repositioning in neurodegeneration: An overview of the use of ambroxol in neurodegenerative diseases.

Drug repositioning in neurodegeneration: An overview of the use of ambroxol in neurodegenerative diseases.

Journal: European journal of pharmacology
Published: April 14, 2020

Altered skeletal muscle glucose-fatty acid flux in amyotrophic lateral sclerosis.

Altered skeletal muscle glucose-fatty acid flux in amyotrophic lateral sclerosis.

Journal: Brain communications
Published: April 09, 2020

Ambroxol Hydrochloride Improves Motor Functions and Extends Survival in a Mouse Model of Familial Amyotrophic Lateral Sclerosis.

Ambroxol Hydrochloride Improves Motor Functions and Extends Survival in a Mouse Model of Familial Amyotrophic Lateral Sclerosis.

Journal: Frontiers in pharmacology
Published: February 21, 2019

Longitudinal transcriptomic analysis of altered pathways in a CHMP2Bintron5-based model of ALS-FTD.

Longitudinal transcriptomic analysis of altered pathways in a CHMP2Bintron5-based model of ALS-FTD.

Journal: Neurobiology of disease
Published: February 05, 2019

Sphingolipid Metabolism Is Dysregulated at Transcriptomic and Metabolic Levels in the Spinal Cord of an Animal Model of Amyotrophic Lateral Sclerosis.

Sphingolipid Metabolism Is Dysregulated at Transcriptomic and Metabolic Levels in the Spinal Cord of an Animal Model of Amyotrophic Lateral Sclerosis.

Journal: Frontiers in molecular neuroscience
Published: October 31, 2017
Showing 1-12 of 38

Last Updated: 09/26/2026