Jean-pierre J. Issa

Oncology
2450 W Hunting Park Ave
Philadelphia, PA 19129

Last Updated: 09/26/2026

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Found 107 publications

Bone marrow immunosuppressive states associate with survival after guadecitabine and atezolizumab therapy in HMA-R/R MDS.

Bone marrow immunosuppressive states associate with survival after guadecitabine and atezolizumab therapy in HMA-R/R MDS.

Journal: Blood neoplasia
Published: January 29, 2026

Defined bacterial consortium highlights the impact of intestinal bacteria on DNA methylation and tumorigenesis.

Defined bacterial consortium highlights the impact of intestinal bacteria on DNA methylation and tumorigenesis.

Journal: Genome biology
Published: December 02, 2025

A phase 1 study of ASTX727 plus talazoparib in patients with triple-negative or hormone resistant/HER2-negative metastatic breast cancer.

A phase 1 study of ASTX727 plus talazoparib in patients with triple-negative or hormone resistant/HER2-negative metastatic breast cancer.

Journal: Cancer
Published: September 28, 2025

EZH2 and intracellular Ca2+ signals interdependently coordinate alloreactive and CAR-T-cell responses.

EZH2 and intracellular Ca2+ signals interdependently coordinate alloreactive and CAR-T-cell responses.

Journal: Cellular & molecular immunology
Published: August 19, 2025

DNA Methylation, Aging, and Cancer.

DNA Methylation, Aging, and Cancer.

Journal: Epigenomes
Published: April 30, 2025

Modeling age-related methylation changes in vitro with intestinal organoids.

Modeling age-related methylation changes in vitro with intestinal organoids.

Journal: BMC biology
Published: April 18, 2025

CDK9 degradation Inhibits Gastroesophageal Cancer growth and Overcomes Radiation Resistance by Increasing Chromatin Accessibility and Downregulating YAP1/TEAD signaling.

CDK9 degradation Inhibits Gastroesophageal Cancer growth and Overcomes Radiation Resistance by Increasing Chromatin Accessibility and Downregulating YAP1/TEAD signaling.

Journal: bioRxiv : the preprint server for biology
Published: March 10, 2025

Bone marrow microenvironment signatures associate with patient survival after guadecitabine and atezolizumab therapy in HMA-resistant MDS.

Bone marrow microenvironment signatures associate with patient survival after guadecitabine and atezolizumab therapy in HMA-resistant MDS.

Journal: bioRxiv : the preprint server for biology
Published: November 28, 2024

ZNFX1 is a Novel Master Regulator in Epigenetically-induced Pathogen Mimicry and Inflammasome Signaling in Cancer.

ZNFX1 is a Novel Master Regulator in Epigenetically-induced Pathogen Mimicry and Inflammasome Signaling in Cancer.

Journal: bioRxiv : the preprint server for biology
Published: November 01, 2024

Publicly Available Dental Image Datasets for Artificial Intelligence.

Publicly Available Dental Image Datasets for Artificial Intelligence.

Journal: Journal of dental research
Published: October 18, 2024

A phase 2 study of decitabine with or without carboplatin and arsenic trioxide in patients with MDS and AML.

A phase 2 study of decitabine with or without carboplatin and arsenic trioxide in patients with MDS and AML.

Journal: Blood neoplasia
Published: July 01, 2024

Association between gut microbiota and CpG island methylator phenotype in colorectal cancer.

Association between gut microbiota and CpG island methylator phenotype in colorectal cancer.

Journal: Gut microbes
Published: June 11, 2024
Showing 1-12 of 107

Last Updated: 09/26/2026