Jeng Y. Chan

St Vincent's Hospital
Sydney, NSW 2010, Australia

Last Updated: 09/26/2026

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Found 15 publications

Tau suppresses microtubule-regulated pancreatic insulin secretion.

Tau suppresses microtubule-regulated pancreatic insulin secretion.

Journal: Molecular psychiatry

Published: February 03, 2023

The Role of Fatty Acid Signaling in Islet Beta-Cell Adaptation to Normal Pregnancy.

The Role of Fatty Acid Signaling in Islet Beta-Cell Adaptation to Normal Pregnancy.

Journal: Frontiers in endocrinology

Published: October 21, 2021

XBP1 maintains beta cell identity, represses beta-to-alpha cell transdifferentiation and protects against diabetic beta cell failure during metabolic stress in mice.

XBP1 maintains beta cell identity, represses beta-to-alpha cell transdifferentiation and protects against diabetic beta cell failure during metabolic stress in mice.

Journal: Diabetologia

Published: September 08, 2021

Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans.

Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans.

Journal: Diabetologia

Published: June 11, 2019

Phlda3 regulates beta cell survival during stress.

Phlda3 regulates beta cell survival during stress.

Journal: Scientific reports

Published: February 21, 2019

Macrophage alterations in islets of obese mice linked to beta cell disruption in diabetes.

Macrophage alterations in islets of obese mice linked to beta cell disruption in diabetes.

Journal: Diabetologia

Published: November 02, 2018

Deletion distal to the PAX6 coding region reveals a novel basis for familial cosegregation of aniridia and diabetes mellitus.

Deletion distal to the PAX6 coding region reveals a novel basis for familial cosegregation of aniridia and diabetes mellitus.

Journal: Diabetes research and clinical practice

Published: September 21, 2018

On-target action of anti-tropomyosin drugs regulates glucose metabolism.

On-target action of anti-tropomyosin drugs regulates glucose metabolism.

Journal: Scientific reports

Published: November 30, 2017

Inhibition of Y1 receptor signaling improves islet transplant outcome.

Inhibition of Y1 receptor signaling improves islet transplant outcome.

Journal: Nature communications

Published: May 23, 2017

Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells.

Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells.

Journal: Diabetologia

Published: October 26, 2015

A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes.

A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes.

Journal: PLoS genetics

Published: February 26, 2015

The balance between adaptive and apoptotic unfolded protein responses regulates β-cell death under ER stress conditions through XBP1, CHOP and JNK.

The balance between adaptive and apoptotic unfolded protein responses regulates β-cell death under ER stress conditions through XBP1, CHOP and JNK.

Journal: Molecular and cellular endocrinology

Published: February 11, 2015

Showing 1-12 of 15

Last Updated: 09/26/2026