Jennie R. Roberts

Oncology R&D, AstraZeneca
Cambridge, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 34 publications

Computed Tomography and Magnetic Resonance Imaging Findings in Early Glioblastoma (e-GBM): Spotting the Wolf in Sheep's Clothing.

Computed Tomography and Magnetic Resonance Imaging Findings in Early Glioblastoma (e-GBM): Spotting the Wolf in Sheep's Clothing.

Journal: Cureus

Published: September 19, 2025

A pilot safety and tolerability study of scanning ultrasound as a neuromodulation therapy in Alzheimer's disease.

A pilot safety and tolerability study of scanning ultrasound as a neuromodulation therapy in Alzheimer's disease.

Journal: Brain communications

Published: July 13, 2025

Achieving human brain exposure with the oral ataxia-telangiectasia mutated kinase inhibitor AZD1390, a substrate of aldehyde oxidase.

Achieving human brain exposure with the oral ataxia-telangiectasia mutated kinase inhibitor AZD1390, a substrate of aldehyde oxidase.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: February 16, 2025

TNF-α signals through ITK-Akt-mTOR to drive CD4+ T cell metabolic reprogramming, which is dysregulated in rheumatoid arthritis.

TNF-α signals through ITK-Akt-mTOR to drive CD4+ T cell metabolic reprogramming, which is dysregulated in rheumatoid arthritis.

Journal: Science signaling

Published: April 23, 2024

Iron deficiency causes aspartate-sensitive dysfunction in CD8+ T cells.

Iron deficiency causes aspartate-sensitive dysfunction in CD8+ T cells.

Journal: Nature communications

Published: January 29, 2024

Intracrine FFA4 signaling controls lipolysis at lipid droplets.

Intracrine FFA4 signaling controls lipolysis at lipid droplets.

Journal: Nature chemical biology

Published: July 26, 2023

VHL-deficiency leads to reductive stress in renal cells.

VHL-deficiency leads to reductive stress in renal cells.

Journal: Free radical biology & medicine

Published: May 17, 2023

Residual Complex I activity and amphidirectional Complex II operation support glutamate catabolism through mtSLP in anoxia.

Residual Complex I activity and amphidirectional Complex II operation support glutamate catabolism through mtSLP in anoxia.

Journal: Scientific reports

Published: May 05, 2023

The glutamate/aspartate transporter EAAT1 is crucial for T-cell acute lymphoblastic leukemia proliferation and survival.

The glutamate/aspartate transporter EAAT1 is crucial for T-cell acute lymphoblastic leukemia proliferation and survival.

Journal: Haematologica

Published: May 03, 2023

LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic β cells.

LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic β cells.

Journal: Cell reports

Published: March 16, 2023

Multiomics analysis couples mRNA turnover and translational control of glutamine metabolism to the differentiation of the activated CD4+ T cell.

Multiomics analysis couples mRNA turnover and translational control of glutamine metabolism to the differentiation of the activated CD4+ T cell.

Journal: Scientific reports

Published: July 15, 2022

NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency.

NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency.

Journal: Cell reports

Published: March 03, 2022

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Last Updated: 09/26/2026