Jennifer L. Small-Saunders

Infectious Disease

630 W 168th St
New York, NY 10032

Last Updated: 09/26/2026

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Found 19 publications

Double Mutations in Plasmodium falciparum Kelch13 drive resistance to next-generation artemisinin derivatives in malaria parasites.

Double Mutations in Plasmodium falciparum Kelch13 drive resistance to next-generation artemisinin derivatives in malaria parasites.

Journal: bioRxiv : the preprint server for biology

Published: April 10, 2026

Structural basis for host membrane binding and remodeling by invading malaria parasites.

Structural basis for host membrane binding and remodeling by invading malaria parasites.

Journal: Cell

Published: November 17, 2025

Identification of genetic markers of quinine partial resistance in Plasmodium falciparum.

Identification of genetic markers of quinine partial resistance in Plasmodium falciparum.

Journal: Nature microbiology

Published: April 10, 2025

Effects of recombination on multi-drug resistance evolution in Plasmodium falciparum malaria.

Effects of recombination on multi-drug resistance evolution in Plasmodium falciparum malaria.

Journal: PLoS computational biology

Published: January 10, 2025

Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission.

Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission.

Journal: Science advances

Published: December 06, 2024

Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance.

Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance.

Journal: Science (New York, N.Y.)

Published: November 28, 2024

Plasmodium falciparum quinine resistance is multifactorial and includes a role for the drug/metabolite transporters PfCRT and DMT1.

Plasmodium falciparum quinine resistance is multifactorial and includes a role for the drug/metabolite transporters PfCRT and DMT1.

Journal: bioRxiv : the preprint server for biology

Published: October 10, 2024

Plasmodium falciparum African PfCRT Mutant Isoforms Conducive to Piperaquine Resistance Are Infrequent and Impart a Major Fitness Cost.

Plasmodium falciparum African PfCRT Mutant Isoforms Conducive to Piperaquine Resistance Are Infrequent and Impart a Major Fitness Cost.

Journal: The Journal of infectious diseases

Published: August 26, 2024

Additional PfCRT mutations driven by selective pressure for improved fitness can result in the loss of piperaquine resistance and altered Plasmodium falciparum physiology.

Additional PfCRT mutations driven by selective pressure for improved fitness can result in the loss of piperaquine resistance and altered Plasmodium falciparum physiology.

Journal: mBio

Published: December 07, 2023

tRNA modification reprogramming contributes to artemisinin resistance in Plasmodium falciparum.

tRNA modification reprogramming contributes to artemisinin resistance in Plasmodium falciparum.

Journal: Nature microbiology

Published: July 05, 2023

Mutant PfCRT Can Mediate Piperaquine Resistance in African Plasmodium falciparum With Reduced Fitness and Increased Susceptibility to Other Antimalarials.

Mutant PfCRT Can Mediate Piperaquine Resistance in African Plasmodium falciparum With Reduced Fitness and Increased Susceptibility to Other Antimalarials.

Journal: The Journal of infectious diseases

Published: July 18, 2022

Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance.

Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance.

Journal: PLoS pathogens

Published: September 21, 2021

Showing 1-12 of 19

Last Updated: 09/26/2026