Jenny W. Roy

Quebec, QC G1V0A6, Canada

Last Updated: 09/26/2026

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Found 50 publications

Synthesis and Biological Evaluation of a Series of N-Substituted Pyruvamide 4-Allylthiosemicarbazones and Their Copper(II) Complexes: Antibacterial, Antiradical, and Antiproliferative Activities.

Synthesis and Biological Evaluation of a Series of N-Substituted Pyruvamide 4-Allylthiosemicarbazones and Their Copper(II) Complexes: Antibacterial, Antiradical, and Antiproliferative Activities.

Journal: Molecules (Basel, Switzerland)

Published: June 30, 2026

Developing Potential Endocrine Therapy Controlling Estradiol and DHT by Targeting 17β-HSD7 Against ER+ Breast Cancer.

Developing Potential Endocrine Therapy Controlling Estradiol and DHT by Targeting 17β-HSD7 Against ER+ Breast Cancer.

Journal: Cells

Published: May 11, 2026

Aminosteroid RM-581 Induces G0/G1 Arrest and Endoplasmic Reticulum Stress-Mediated Apoptosis in Human Acute and Chronic Leukemia Cell Lines.

Aminosteroid RM-581 Induces G0/G1 Arrest and Endoplasmic Reticulum Stress-Mediated Apoptosis in Human Acute and Chronic Leukemia Cell Lines.

Journal: Cancers

Published: February 21, 2026

Tris[N-(prop-2-en-1-yl)hydrazinecarbothioamide]-Cobalt(III) Chloride as a Stimulator of the Total Antioxidant Status of Apis mellifera with Acaricidal Activity.

Tris[N-(prop-2-en-1-yl)hydrazinecarbothioamide]-Cobalt(III) Chloride as a Stimulator of the Total Antioxidant Status of Apis mellifera with Acaricidal Activity.

Journal: Antioxidants (Basel, Switzerland)

Published: November 14, 2025

Metabolite profiling in human and mouse liver microsomes of the aminosteroid RM-581, a new orally active anticancer agent.

Metabolite profiling in human and mouse liver microsomes of the aminosteroid RM-581, a new orally active anticancer agent.

Journal: Bioorganic chemistry

Published: June 18, 2025

Aminosteroid RM-581 Decreases Cell Proliferation of All Breast Cancer Molecular Subtypes, Alone and in Combination with Breast Cancer Treatments.

Aminosteroid RM-581 Decreases Cell Proliferation of All Breast Cancer Molecular Subtypes, Alone and in Combination with Breast Cancer Treatments.

Journal: Journal of clinical medicine

Published: May 15, 2023

An Aminosteroid Derivative Shows Higher In Vitro and In Vivo Potencies than Gold Standard Drugs in Androgen-Dependent Prostate Cancer Models.

An Aminosteroid Derivative Shows Higher In Vitro and In Vivo Potencies than Gold Standard Drugs in Androgen-Dependent Prostate Cancer Models.

Journal: Cancers

Published: April 01, 2023

Chemical Synthesis and Biological Evaluation of 3-Substituted Estrone/Estradiol Derivatives as 17β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors Acting via a Reverse Orientation of the Natural Substrate Estrone.

Chemical Synthesis and Biological Evaluation of 3-Substituted Estrone/Estradiol Derivatives as 17β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors Acting via a Reverse Orientation of the Natural Substrate Estrone.

Journal: Molecules (Basel, Switzerland)

Published: December 01, 2022

Chemical synthesis of fluorinated and iodinated 17β-HSD3 inhibitors and evaluation for imaging prostate cancer tumors and tissue biodistribution.

Chemical synthesis of fluorinated and iodinated 17β-HSD3 inhibitors and evaluation for imaging prostate cancer tumors and tissue biodistribution.

Journal: Bioorganic chemistry

Published: June 20, 2022

Chemical synthesis, NMR characterization, and anticancer activity of androstene derivatives with a C17-side chain.

Chemical synthesis, NMR characterization, and anticancer activity of androstene derivatives with a C17-side chain.

Journal: Steroids

Published: March 19, 2022

An irreversible inhibitor of 17β-hydroxysteroid dehydrogenase type 1 inhibits estradiol synthesis in human endometriosis lesions and induces regression of the non-human primate endometriosis.

An irreversible inhibitor of 17β-hydroxysteroid dehydrogenase type 1 inhibits estradiol synthesis in human endometriosis lesions and induces regression of the non-human primate endometriosis.

Journal: The Journal of steroid biochemistry and molecular biology

Published: March 09, 2022

Induction of Endoplasmic Reticulum Stress-Mediated Apoptosis by Aminosteroid RM-581 Efficiently Blocks the Growth of PC-3 Cancer Cells and Tumors Resistant or Not to Docetaxel.

Induction of Endoplasmic Reticulum Stress-Mediated Apoptosis by Aminosteroid RM-581 Efficiently Blocks the Growth of PC-3 Cancer Cells and Tumors Resistant or Not to Docetaxel.

Journal: International journal of molecular sciences

Published: August 07, 2021

Showing 1-12 of 50

Last Updated: 09/26/2026