Jens-ulrich Rahfeld - Publications

Early Binding of Anti-Amyloid Antibodies to CAA Drives Complement Activation, Inflammation and ARIA in Mice.

Journal: bioRxiv : the preprint server for biology

Published: March 23, 2026

Early binding of anti-amyloid antibodies to CAA drives complement activation, inflammation and ARIA in mice.

Journal: Molecular neurodegeneration

Published: March 04, 2026

Identification of isoaspartate-modified transthyretin as potential target for selective immunotherapy of transthyretin amyloidosis.

Journal: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis

Published: May 27, 2024

Consequences of Amyloid-β Deficiency for the Liver.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: October 15, 2023

Contribution of amino acids in the active site of dipeptidyl peptidase 4 to the catalytic action of the enzyme.

Journal: PloS one

Published: July 12, 2023

Evidence for Enhanced Efficacy of Passive Immunotherapy against Beta-Amyloid in CD33-Negative 5xFAD Mice.

Journal: Biomolecules

Published: January 28, 2022

Tetrahydroimidazo[4,5-c]pyridine-Based Inhibitors of Porphyromonas gingivalis Glutaminyl Cyclase.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: October 15, 2021

Combination of the Glutaminyl Cyclase Inhibitor PQ912 (Varoglutamstat) and the Murine Monoclonal Antibody PBD-C06 (m6) Shows Additive Effects on Brain Aβ Pathology in Transgenic Mice.

Journal: International journal of molecular sciences

Published: September 06, 2021

CD33-directed immunotherapy with third-generation chimeric antigen receptor T cells and gemtuzumab ozogamicin in intact and CD33-edited acute myeloid leukemia and hematopoietic stem and progenitor cells.

Journal: International journal of cancer

Published: March 01, 2021

Mammalian-like type II glutaminyl cyclases in Porphyromonas gingivalis and other oral pathogenic bacteria as targets for treatment of periodontitis.

Journal: The Journal of biological chemistry

Published: November 19, 2020

Targeting isoaspartate-modified Aβ rescues behavioral deficits in transgenic mice with Alzheimer's disease-like pathology.

Journal: Alzheimer's research & therapy

Published: May 07, 2020

Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life.

Journal: Nature neuroscience

Published: February 11, 2020