Jeremy S. Lee

107 Wiggins Road, S7N 0W0
Saskatoon, SK, Canada

Last Updated: 09/26/2026

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Found 16 publications

An HPLC-UV validated bioanalytical method for measurement of in vitro phase 1 kinetics of α-synuclein binding bifunctional compounds.

An HPLC-UV validated bioanalytical method for measurement of in vitro phase 1 kinetics of α-synuclein binding bifunctional compounds.

Journal: Xenobiotica; the fate of foreign compounds in biological systems

Published: October 25, 2022

Employing in vitro metabolism to guide design of F-labelled PET probes of novel α-synuclein binding bifunctional compounds.

Employing in vitro metabolism to guide design of F-labelled PET probes of novel α-synuclein binding bifunctional compounds.

Journal: Xenobiotica; the fate of foreign compounds in biological systems

Published: June 30, 2021

Adenosine A1 receptor ligands bind to α-synuclein: implications for α-synuclein misfolding and α-synucleinopathy in Parkinson's disease.

Adenosine A1 receptor ligands bind to α-synuclein: implications for α-synuclein misfolding and α-synucleinopathy in Parkinson's disease.

Journal: Translational neurodegeneration

Published: December 07, 2020

Novel Dimer Compounds That Bind α-Synuclein Can Rescue Cell Growth in a Yeast Model Overexpressing α-Synuclein. A Possible Prevention Strategy for Parkinson's Disease.

Novel Dimer Compounds That Bind α-Synuclein Can Rescue Cell Growth in a Yeast Model Overexpressing α-Synuclein. A Possible Prevention Strategy for Parkinson's Disease.

Journal: ACS chemical neuroscience

Published: September 28, 2016

Behavior of α-synuclein-drug complexes during nanopore analysis with a superimposed AC field.

Behavior of α-synuclein-drug complexes during nanopore analysis with a superimposed AC field.

Journal: Electrophoresis

Published: May 31, 2016

Drugs That Bind to α-Synuclein: Neuroprotective or Neurotoxic?

Drugs That Bind to α-Synuclein: Neuroprotective or Neurotoxic?

Journal: ACS chemical neuroscience

Published: September 18, 2015

Superposition of an AC field improves the discrimination between peptides in nanopore analysis.

Superposition of an AC field improves the discrimination between peptides in nanopore analysis.

Journal: The Analyst

Published: February 21, 2015

A distinct triplex DNA unwinding activity of ChlR1 helicase.

A distinct triplex DNA unwinding activity of ChlR1 helicase.

Journal: The Journal of biological chemistry

Published: January 07, 2015

Rasagiline, a suicide inhibitor of monoamine oxidases, binds reversibly to α-synuclein.

Rasagiline, a suicide inhibitor of monoamine oxidases, binds reversibly to α-synuclein.

Journal: ACS chemical neuroscience

Published: December 17, 2014

The use of nanopore analysis for discovering drugs which bind to α-synuclein for treatment of Parkinson's disease.

The use of nanopore analysis for discovering drugs which bind to α-synuclein for treatment of Parkinson's disease.

Journal: European journal of medicinal chemistry

Published: April 28, 2014

Cu(II) and dopamine bind to α-synuclein and cause large conformational changes.

Cu(II) and dopamine bind to α-synuclein and cause large conformational changes.

Journal: The FEBS journal

Published: October 31, 2013

RNase A does not translocate the alpha-hemolysin pore.

RNase A does not translocate the alpha-hemolysin pore.

Journal: PloS one

Published: October 22, 2013

Showing 1-12 of 16

Last Updated: 09/26/2026