Jeroen Schaap-Elassaiss
Utrecht, UT 3512HB, Netherlands
Last Updated: 09/26/2026
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Found 22 publications
On the coupling between a basic FcRn mechanism and target-mediated disposition of antibodies.
Journal: Journal of pharmacokinetics and pharmacodynamics
Published: May 13, 2025
Network modeling of sporadic colorectal cancer reveals the importance of off-target effects of Cyclooxygenase inhibitors.
Journal: NPJ systems biology and applications
Published: April 10, 2025
Application of a Nociceptive Test Battery to Assess Potential Synergy between Two Analgesics in Healthy Subjects.
Journal: ACS pharmacology & translational science
Published: November 28, 2024
Stronger together: a cross-SIG perspective on improving drug development.
Journal: Journal of pharmacokinetics and pharmacodynamics
Published: October 03, 2024
An asymptotic description of a basic FcRn-regulated clearance mechanism and its implications for PBPK modelling of large antibodies.
Journal: Journal of pharmacokinetics and pharmacodynamics
Published: January 18, 2024
Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice.
Journal: Pharmaceutical research
Published: May 16, 2023
The PBPK LeiCNS-PK3.0 framework predicts Nirmatrelvir (but not Remdesivir or Molnupiravir) to achieve effective concentrations against SARS-CoV-2 in human brain cells.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Published: August 03, 2022
Drug Distribution in Brain and Cerebrospinal Fluids in Relation to IC50 Values in Aging and Alzheimer's Disease, Using the Physiologically Based LeiCNS-PK3.0 Model.
Journal: Pharmaceutical research
Published: January 14, 2022
Lumbar cerebrospinal fluid-to-brain extracellular fluid surrogacy is context-specific: insights from LeiCNS-PK3.0 simulations.
Journal: Journal of pharmacokinetics and pharmacodynamics
Published: January 12, 2021
Variability in the Log Domain and Limitations to Its Approximation by the Normal Distribution.
Journal: CPT: pharmacometrics & systems pharmacology
Published: November 20, 2019
Correction: Baseline Tumor Size Is an Independent Prognostic Factor for Overall Survival in Patients with Melanoma Treated with Pembrolizumab.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: December 05, 2018
Baseline Tumor Size Is an Independent Prognostic Factor for Overall Survival in Patients with Melanoma Treated with Pembrolizumab.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: August 15, 2017
Last Updated: 09/26/2026