Jerson L. Silva

Rio De Janeiro, RJ, Brazil

Last Updated: 09/26/2026

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Found 30 publications

Cancer-linked aggregation of p53 is driven by sequence-encoded frustration, solvation, and hydrophobic gating absent in its paralogs.

Cancer-linked aggregation of p53 is driven by sequence-encoded frustration, solvation, and hydrophobic gating absent in its paralogs.

Journal: Communications chemistry

Published: October 09, 2025

Oncogenic p53 triggers amyloid aggregation of p63 and p73 liquid droplets.

Oncogenic p53 triggers amyloid aggregation of p63 and p73 liquid droplets.

Journal: Communications chemistry

Published: June 07, 2024

Effect of quercetin and chrysin and its association on viability and cell cycle progression in MDA-MB-231 and MCF-7 human breast cancer cells.

Effect of quercetin and chrysin and its association on viability and cell cycle progression in MDA-MB-231 and MCF-7 human breast cancer cells.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: May 21, 2024

Nucleic acid actions on abnormal protein aggregation, phase transitions and phase separation.

Nucleic acid actions on abnormal protein aggregation, phase transitions and phase separation.

Journal: Current opinion in structural biology

Published: September 10, 2021

Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands.

Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands.

Journal: Chemical science

Published: June 24, 2021

Exploring the polymorphism, conformational dynamics and function of amyloidogenic peptides and proteins by temperature and pressure modulation.

Exploring the polymorphism, conformational dynamics and function of amyloidogenic peptides and proteins by temperature and pressure modulation.

Journal: Biophysical chemistry

Published: October 02, 2020

Oncogenic Gain of Function in Glioblastoma Is Linked to Mutant p53 Amyloid Oligomers.

Oncogenic Gain of Function in Glioblastoma Is Linked to Mutant p53 Amyloid Oligomers.

Journal: iScience

Published: August 21, 2019

RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction.

RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction.

Journal: Scientific reports

Published: March 21, 2019

Loss of the p53 transactivation domain results in high amyloid aggregation of the Δ40p53 isoform in endometrial carcinoma cells.

Loss of the p53 transactivation domain results in high amyloid aggregation of the Δ40p53 isoform in endometrial carcinoma cells.

Journal: The Journal of biological chemistry

Published: January 15, 2019

Modulation of p53 and prion protein aggregation by RNA.

Modulation of p53 and prion protein aggregation by RNA.

Journal: Biochimica et biophysica acta. Proteins and proteomics

Published: January 05, 2019

Methods to Screen Compounds Against Mutant p53 Misfolding and Aggregation for Cancer Therapeutics.

Methods to Screen Compounds Against Mutant p53 Misfolding and Aggregation for Cancer Therapeutics.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: October 21, 2018

p53 reactivation with induction of massive apoptosis-1 (PRIMA-1) inhibits amyloid aggregation of mutant p53 in cancer cells.

p53 reactivation with induction of massive apoptosis-1 (PRIMA-1) inhibits amyloid aggregation of mutant p53 in cancer cells.

Journal: The Journal of biological chemistry

Published: June 29, 2018

Showing 1-12 of 30

Last Updated: 09/26/2026